General Transcription Factors

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Across
  1. 5. The biochemical process of copying genetic info from a DNA template into an RNA strand.
  2. 7. The general transcription factor responsible for the phosphorylation of the RNA Polymerase II Polypeptide tail to trigger its release from the promoter.
  3. 8. A specific region on the gene promoter that indicates where the transcription initiation complex assembles.
Down
  1. 1. A subunit of TFIID that recognizes and binds to the TATA box sequence to start the assembly process.
  2. 2. The first general transcription factor which contains TBP and assembles at the promoter of a gene to initiate transcription.
  3. 3. The specific DNA region and site where general transcription factors assemble to determine the direction of transcription.
  4. 4. An enzyme that unwinds DNA helix & catalyzes the formation of phosphodiester bonds between nucleotides.
  5. 6. The general transcription factor that binds to the DNA specifically after TFIID has induced a local structural distortion is.