Genetics Crossword

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Across
  1. 3. The region of a gene required for initiating synthesis of an RNA copy (8)
  2. 8. Collective name for chromosomes 1-22 (9)
  3. 11. A change in the base sequence or structure of the DNA, often as a result of damage to DNA (8)
  4. 14. An individual with two different alleles of a gene (12)
  5. 18. This DNA is only inherited from the mother (13)
  6. 20. Type of cell division used for cell proliferation (7)
  7. 21. Failure of chromosomes to segregate / separate during cell division (3,11)
  8. 23. Processing of RNA to generate messenger RNA (8)
  9. 29. The part of a chromosome that has an essential role in ensuring correct segregation during cell division (10)
  10. 30. The sections of a gene that become part of the mature messenger RNA (5)
  11. 31. The sections of a gene that are spliced out of a transcript to generate messenger RNA (7)
  12. 33. A genetic variant that has a frequency of at least 1% in the population (12)
  13. 35. The complete gene sequence for an organism (6)
  14. 36. The ends of chromosomes (9)
  15. 37. Type of cell division used to generate gametes (7)
Down
  1. 1. Where three copies of a particular chromosome are present, instead of the normal two copies (7)
  2. 2. When a mutation is ___________ it takes only one mutant allele to cause disease (8)
  3. 4. Arrangement displaying the chromosomes of an individual in order (9)
  4. 5. When a mutation is ___________ the effect of the mutation will not be seen in the presence of a normal allele (9)
  5. 6. An individual with two identical alleles of a gene (10)
  6. 7. A word used to describe a DNA sequence or structural difference compared to the reference genome (7)
  7. 9. The process of making protein according to the instructions in messenger RNA (11)
  8. 10. The enzyme that makes DNA (3,10)
  9. 11. A modification of DNA which can make genes inactive (11)
  10. 12. One of two or more alternative forms of a DNA sequence or gene (6)
  11. 13. The process by which material can be exchanged between the two copies of a chromosome (13)
  12. 15. A region of repetitive DNA in which the repeat units are about 2-6 base pairs (14)
  13. 16. A group of three bases that codes for a particular amino acid (5)
  14. 17. A deletion or insertion in the coding DNA sequence that alters the way in which the sequence is read (10)
  15. 19. A replicated chromosome consists of two of these (10)
  16. 22. The cellular process in which an RNA copy is made from DNA (13)
  17. 24. The genetic constitution of an organism (8)
  18. 25. The appearance or characteristics of an individual (9)
  19. 26. A condition in which the wrong number of chromosomes are present (10)
  20. 27. A modification of histones which can help gene activation (11)
  21. 28. A region on a chromosome, seen as a light or dark area following staining with Giemsa (4)
  22. 32. The complex of DNA with proteins including histones (9)
  23. 34. Where only one copy of a particular chromosome is present, instead of the normal two copies (8)
  24. 35. The study of genes and inheritance (8)