Across
- 6. are enzymes that can only phosphorylate downstream proteins to activate/deactivate when it is bound with it’s partner cyclin
- 7. genes are involved in ensuring the accurate repair of damaged DNA
- 8. regulate the progression of CDK by inhibiting these molecules
Down
- 1. Genes that have the potential to cause cancer when their activity is abnormally increased, or when their normal function is disrupted
- 2. Proteins that bind cyclin-dependent kinases, activating them
- 3. Disease that derives from uncontrolled growth and division of abnormal cells that have the ability to invade surrounding tissues and spread to other locations in the body via the bloodstream or lymphatic network
- 4. is a class of G-proteins that provides cell-autonomous and non-cell-autonomous cues that promote pro-growth results and inhibit anti-growth signals.
- 5. Describes the type of trait that oncogenes express, many gene mutations are required to generate cancer, NOT just a single mutation in a single gene