Across
- 1. Fragments of a chromosome fused with a different chromosome; can produce oncogenes
- 5. When unmutated this gene functions to stimulate normal cell division
- 7. Enzyme adds to the telomeres of a chromosome, inappropriately active in cancer cells
- 8. Mutations here are able to be passed down in families; can cause earlier development of cancer
- 9. This vital function occurs when a cell is beyond repair; this ability is lost in cancerous cells
Down
- 2. The result of a recessively mutated RB1 tumor suppressor gene
- 3. Proto-oncogene that helps cells progress through the cell cycle when functioning normally
- 4. Mass of cells created by mutated cell cycle checkpoints allowing unregulated division
- 6. Constitutively expressed genes that overproduce proteins promoting cell division