Across
- 3. One of two or more alternate forms of a gene or marker at a particular locus on a chromosome.
- 6. A combination of alleles at closely linked gene loci that are inherited together.
- 7. Apparent earlier age of onset and increased severity of a disease in successive generations, eg, huntington's disease.
- 8. Genetic linkage refers to the observation that two or more genes located on the same chromosome are inherited together.
- 9. In eukaryotes, the basic chromosome set, consisting of a species-specific number of linkage groups and the genes contained therein.
- 10. Single-stranded complementary DNA, ie, a DNA molecule synthesized from a RNA template by reverse transcription of RNA.
Down
- 1. A disorder in which the cause is considered to be a combination of genetic effects
- 2. A single genome or set of chromosomes compared to the normal diploid (double) set of chromosomes.
- 4. The application of epigenetics to the whole genome.
- 5. Heritable changes to DNA structure that do not alter the underlying DNA sequence, eg, DNA methylation.