Across
- 3. Responsible for sensation; affected by pruritus or pain
- 9. Clear zone beneath basal cells of the epidermis, part of the BMZ
- 10. Deepest layer of the epidermis; single row of dividing cells
- 13. Dense, collagen-rich layer within the BMZ
- 17. Main cell type in the epidermis; produces keratin
- 18. Attached to the hair follicle and produces oil; affected in sebaceous adenitis
- 20. The deepest layer of the skin; abscesses or tumors here cause painful swellings
- 22. Specialized structures connecting adjacent cells; provide mechanical strength
- 25. Disorders where the immune system attacks skin components, causing blisters
Down
- 1. Layer above stratum basale; cells connected by desmosomes
- 2. Layer above stratum spinosum; keratinocytes begin to die and accumulate granules
- 4. Proteins targeted by autoantibodies in certain blistering diseases
- 5. Specialized structures anchoring basal keratinocytes to the BMZ
- 6. Bundles of protein filaments inside cells; anchor to desmosomes
- 7. Outermost layer of the epidermis; dead, flattened keratinocytes
- 8. Interface between the epidermis and dermis
- 11. Disorders characterized by extreme skin fragility and blistering due to protein defects
- 12. Found in the dermis and hypodermis; affected by vasculitis or bruising
- 14. Adhesion molecules in the BMZ; help cells stick to each other and the extracellular matrix
- 15. Collagen VII structures securing the dermis to the epidermis
- 16. Process by which keratinocytes become filled with keratin and form the tough outer layer
- 18. Helps regulate temperature; affected by gland hyperplasia or tumors
- 19. Fats found between cells of the stratum corneum; form a waterproof barrier
- 21. Lies just beneath the epidermis; affected by deep pyoderma or allergies
- 23. The outermost layer of the skin, affected in superficial pyoderma
- 24. Extends from the epidermis into the dermis; affected in folliculitis