Glycolysis

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Across
  1. 5. (9 letters) – Pathway mode when O₂ is absent; regenerates NAD⁺ via lactate
  2. 6. (19 letters) – RBC shunt metabolite regulating O₂ affinity of hemoglobin
  3. 7. (7 letters) – End product; enters mitochondria or is reduced to lactate
Down
  1. 1. (11 letters) – Liver isoform with high Km, regulated by insulin
  2. 2. (6 letters) – Converts 2-phosphoglycerate to phosphoenolpyruvate (PEP)
  3. 3. (19 letters) – Rate-limiting, allosterically regulated enzyme (PFK-1)
  4. 4. dehydrogenase (35 letters) – Oxidizes G3P, produces NADH and 1,3-BPG