Group 2: The Biology of Cancer

123456789101112131415161718192021222324252627282930
Across
  1. 2. Increase in cell number leading to tissue enlargement
  2. 5. Protein that regulates progression through the cell cycle
  3. 6. Protein complex that holds sister chromatids together
  4. 8. Agent that causes DNA mutations
  5. 10. Cancerous tumors
  6. 12. The type of cancer that arises from cells derived from the mesenchyme
  7. 15. Mutated genes that drive cancerous growth
  8. 17. Non-cancerous tumors
  9. 18. Sample of tissue taken for diagnosis
  10. 19. Programmed cell death
  11. 20. Cancer of blood-forming tissues and bone marrow
  12. 23. Kinase activated by a boulder strand break
  13. 26. Normal gene that can become an oncogene when mutated
  14. 27. Abnormal mass of tissue resulting from uncontrolled cell division
  15. 28. Stalled replication fork activates which kinase
  16. 29. Cleaves the cohesin complex
  17. 30. Factor Signaling molecules that stimulate cell division and survival
Down
  1. 1. The type of cancer that arises from epithelial cells
  2. 3. ____ Stem Cell: has unlimited self-renewal and differentiation potential
  3. 4. Surgery removing the uterus for patients with endometrial cancer
  4. 6. Family of enzymes that DEPEND ON CYCLIN!
  5. 7. A substance that can increase cancer risk
  6. 8. When cancerous cells spread from their point of origin to distant parts of the body
  7. 9. Cancer of the lymphatic system
  8. 11. Loss of differentiation seen in malignant cells
  9. 13. A process in which tumors can have access to the blood supply
  10. 14. Low oxygen environment
  11. 16. The process of determining how far cancer has spread within the body
  12. 21. ___ cells. They line the surfaces of the body, forming a protective barrier on organs, skin, and blood vessels
  13. 22. Experiment technique that allows you to measure gene expression of lots of genes at the same time
  14. 24. Enzyme that extends chromosome ends and enables unlimited division
  15. 25. A virus that integrates into the host genome, disrupting normal cell function and division potentially leading to cancer