Across
- 2. Nuclei richly innervated by projections from ARC. Main site of CRH and TRH
- 5. works opposite to leptin, protective against obesity
- 6. targets neurons in ARC to decrease food intake
- 8. The colony of microorganisms that has major beneficial and harmful effects on health
- 12. (three words) elevated levels of hormones/opioids target the ___ during critical windows of neuronal development, leading to an increased preference of suboptimal dietary molecules
- 13. abv. feeding intravenously, bypassing the gut
- 14. Cell type that produce gastro-intestinal hormones that influence GI secretion, motility or postprandial satiety
- 15. unregulated during periods of rapid growth, hunger signal
- 17. Columnar cell type with innate immune function, associated with microbial defence - provide protection to stem cells
- 19. immune cells present in 2nd trimester
- 20. (three words) generates peristaltic waves
- 21. abv. associated with immature digestive function and leads to problems transitioning from parenteral to enteral nutrition
- 22. (three words)what we experience in utero can help reveal and underlying vulnerability if there is a second hit postnatally
Down
- 1. failure of gut to return to abdominal cavity, covered by sac
- 3. Most potent trophic stimulus of GIT growth
- 4. Cell type located in middle of crypt to tip of villus, secretion of mucus. Characterized by specific mucus granules in cytoplasm
- 7. Nuclei that interacts with peripheral circulation from brain and gut. Integrates hormonal signals for energy homeostasis
- 9. hormonal cues in this liquid may programme appetite regulation
- 10. (two words)clears microorganisms, antigens and other toxic substances from prolonged contact with GI epithelium
- 11. abv. inflammation/infection that causes destruction of the bowel
- 16. Most abundant intestinal epithelial cell, hydrolytic and absorptive function, involved in innate immune response
- 18. An increase in _____ before and during birth is a trigger for gut functional development