Heart Drugs

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Across
  1. 7. Heparin INR measured by
  2. 9. calcium channel blocker, first line drug for Black ethnicities
  3. 10. Na+ channel blocker, may prolong QT interval
  4. 12. ACE inhibitor, activated by liver enzymes
  5. 15. Wafarin INR measured by
  6. 17. Activates antithrombin which inhibits prothrombin -> thrombin
  7. 19. BB that may cause bradycardia, hypotension and erectile dysfunction
  8. 20. Increases vagal stimulation = negative chronotrope, inhibits Na+/K+-ATPase = positive inotrope
  9. 21. antiplatelet MoA TXA2 antagonist
Down
  1. 1. ARB antagonist
  2. 2. Antiplatelet that inhibits P2Y12 receptors
  3. 3. Beta blocker and K+ channel inhibitor,rate and rhythm control drug, used to extinguish tachyarrhythmias,may cause pulmonary fibrosis, thyroid dysfunction and torsade de pointes
  4. 4. CCB, rate and rhythm control, cannot be prescribed with sodium channel blocker, may cause rebound tachycardia
  5. 5. anticoagulant that inhibits Vitamin K epoxide reductase
  6. 6. funny current inhibitor
  7. 8. DOAC that inhibits Factor Xa to stop formation of thrombin
  8. 11. Clot buster, activates plasmin
  9. 13. NO to induce vasodilation
  10. 14. Beta-1 blocker, contraindicated for asthma, first line for torsade de pointes
  11. 16. vasodilator by increase of cGMP
  12. 18. hyperpolarises AVN, used in acute settings