Across
- 1. a localized collection of blood, usually clotted (decreased platelets or clotting factors resulting in hemorrhage into the skin, vascular abnormalities, break in blood vessel walls resulting from trauma)
- 6. a tumor arising from myeloid tissue and containing a pale green pigment (acute myelogenous leukemia that has infiltrated the skin)
- 10. prominent on the malleoli on the ankles (sickle cell disease)
- 13. any of a small group of conditions characterized by ecchymosis or other small hemorrhages in skin and mucous membranes (decreased platelets or clotting factors resulting in hemorrhage into the skin, vascular abnormalities, break in blood vessel walls resulting from trauma)
- 15. palpable spleen (anemia, thrombocytopenia, leukemia, lymphomas, leukopenia, mononucleosis, malaria, cirrhosis, trauma, portal hypertension)
- 16. lacking physical strength or energy (anemia)
- 17. numbness sensation and extreme sensitivity experienced in central and peripheral nerves, impaired muscle movement (vitamin B12 deficiency or folate deficiency)
- 19. form of telangiectasia characterized by a round red central portion and branching radiations resembling the profile of a spider, usually develop on face, neck and chest (elevated estrogen levels as in pregnancy or liver disease)
- 22. tongue surface smooth and shiny, mucosa thin and red from decreased papillae (pernicious anemia, iron-deficiency anemia)
- 23. O2 carrying capacity as reflected by the O2 sat by pulse oximetry (O2 sat may be decreased in cases of severe anemia)
- 24. a larger than normal abdominal profile, may be soft or firm, tender or nontender, and accompanied by other symptoms such as nausea, vomiting, or rebound tenderness (lymphoma, may manifest as abdominal adenopathy, mass/masses or bowel obstruction)
- 25. decreased visual acuity or areas of blindness (anemia, extreme leukocytosis, excessive clotting, thrombocytopenia)
- 28. pain in pelvis, ribs, spine, sternum (multiple myeloma related to enlarged tumors that stretch periosteum; bone invasion by leukemia cells)
- 30. paleness, decreased or absence of coloration in the conjunctiva (anemia)
- 32. paleness, decreased or absence of skin coloration (anemia)
- 34. yellow appearance of the sclera (accumulation of bile pigment resulting from rapid or excessive hemolysis or liver disease or infiltration)
- 35. small hemorrhagic spot, larger than petechiae; nonelevated, round and irreguar (decreased platelets or clotting factors resulting in hemorrhage into the skin, vascular abnormalities, break in blood vessel walls resulting from trauma)
- 36. transient, episodic redness of skin (usually around face and neck) (anemia)
Down
- 2. joint pain (sickle cell disease from hemarthrsis)
- 3. pallor, ulceration, swelling, or bleeding of gums (anemia, neutropenia, inability of impaired leukocytes to combat oral infections)
- 4. scratch or abrasion of skin (scratching from intense pruritus)
- 5. small angioma with tendency to bleed, focal red lesions, coarse or fine red lines (dilation of small vessels)
- 7. heart rate greater than 100 beats/minute (compensatory mechanism in anemia to increase cardiac output)
- 8. palpable liver (leukemia, cirrhosis, or fibrosis secondary to iron overload from sickle cell disease or thalassemia)
- 9. Hypertension:>140/90 mm Hg; Hypotension:<90 mm Hg systolic or >40 mm Hg drop from baseline; orthostasis: heart rate >20 beats/min increase or blood pressure >20 mm Hg decrease from baseline when moving from a lying position to either sitting or standing (common manifestation in anemia)
- 11. yellow appearance of skin and mucous membrane (accuulation of bile pigment:hemolysis or liver damage)
- 12. fluid-filled spaces surrounding the joints (occurs with hemophilia and sickle cell anemia as bleeding occurs in the the joint causing inflammation)
- 14. unpleasant cutaneous sensation that provokes the desire to rub or scratch the skin (Hodgkin's lymphoma)
- 18. pain in the cranium, potentially involving one area or extending from the frontal area to the back of the neck (common manifestation of mild to moderate anemia, may signal intracranial hemorrhage)
- 20. benign tumor consisting of blood or lymph vessels (most are congenital)
- 21. spontaneous bleeding from the nares (may occur with low platelet count)
- 22. abnormal sensitivity to touch or pressure on sternum (leukemia resuling from increased bone marrow cellularity)
- 26. lymph nodes enlarged, greater than 1cm, may be tender to touch (infection, foreign infiltrations)
- 27. Pinpoint, nonraised, perfectly round area >2mm, purple, dark red, or brown(decreased platelets or clotting factors resulting in hemorrhage into the skin, vascular abnormalities, break in blood vessel walls resulting from trauma)
- 29. a tumor arising from abnormal plasma cells (multiple myeloma that has infiltrated tissue)
- 31. feeling the heartbeat, flutter or pound in the chest (anemia, fluid volume overload, hypertension, dysrhythmias)
- 33. bluish discoloration of skin and mucous membranes (deoxyhemoglobin in blood)