Hematopoiesis

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Across
  1. 1. The gene that is most commonly mutated in PMF.
  2. 4. The blood cells involved in the immune response in the body.
  3. 6. The white blood cells that do not circulate regularly, but are released from the bone marrow as part of an immune response.
  4. 7. There are two systems for classifying AML: BLANK and WHO.
  5. 11. The part of blood responsible for clotting.
  6. 13. What kind of cells are produced by B cells?
  7. 14. How many major subtypes of leukemia are there?
  8. 15. How many types of T-cells are there?
  9. 17. The type of leukemia that produces partly matured cells that look ~normal, but do not function well.
  10. 19. A disorder whereby myeloid cells and fibroblasts are overproduced.
  11. 21. Where the bone marrow is found in the bones.
  12. 22. The lineage of blood cells that include the rbc, platelets, mast cells, monocytes, and granulocytes.
  13. 24. A malignancy of the cells.
  14. 27. What cell type forms thrombocytes?
  15. 30. The chromosome that is found in 95% of CML cases.
  16. 32. The place where blood forms in the earliest embryonic stage.
  17. 33. The lineage of blood cells that includes the B, T, and NK cells.
  18. 34. The model that we use to study embryonic hematopoiesis.
  19. 35. The cells involved in the allergic response.
  20. 37. The thing that is lacking in erythrocytes and thrombocytes.
  21. 38. The largest blood cells
Down
  1. 2. The type of leukemia that grows faster but is easier to treat.
  2. 3. The RBC found in PMF patients have this abnormal shape as a feature of the disease.
  3. 5. The red blood cells that carry oxygen and carbon dioxide.
  4. 7. The most common type of blood cancer, which can originate in bone marrow and lymph organs.
  5. 8. The formation of blood cells occurs via BLANK.
  6. 9. The stage of blood development whereby blood develops in blood vessels.
  7. 10. The cells that have a tree-like appearance. They may be from the myeloid lineage, but it is unclear. They display antigens for T-cells.
  8. 12. An irregularly-shaped cell, it may be involved in inflammation and may regulate helper T-cells.
  9. 16. All cancers are BLANKs.
  10. 18. The cell type that is overproduced in FL.
  11. 20. The most common immune cell.
  12. 23. The stage of hematopoiesis in the fetus where both the myeloid and lymphoid lineage cells start dividing.
  13. 25. The kind of cell that comes from monocytes.
  14. 26. The stage of blood development that starts at the 5th month.
  15. 28. The bone marrow type where blood is formed post-natally.
  16. 29. An immune cell with a double-lobed nucleus that may defend against parasites.
  17. 31. The lymphoid cells that mature in the thymus.
  18. 36. A co-stimulatory molecule that can activate lymphocytes.