hematopoiesis

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Across
  1. 1. Morphologically distinguishable also classified as blasts and more mature forms.
  2. 5. loose aggregates of lymphoid cells or tissues throughout the body.
  3. 6. enhanced killing of malignant cells.
  4. 8. Nodes carry lymph & act as filters to remove foreign from the lymph by phagocytosis.
  5. 10. when two cells derived from the same precursor take different routes of development.
  6. 11. hematopoietic microenvironment are lining cells.
  7. 12. hematopoietic growth factors, colony-stimulating factors (CSFs), interleukins (IL), interforns.
  8. 14. programmed cell death.
  9. 16. acquisition of specialized functions in cells.
  10. 20. serves as a compartment for T cell maturation.
  11. 22. its a sac responsible of the production of RBCs and macrophages.
  12. 23. are cells that regulate and support hematopoiesis cells.
  13. 24. primary site of cell production at 3 months.
  14. 25. A type of marrow that found in long bone and gradually replaced by adipocytes yellow marrow.
  15. 26. early site of hematopoiesis , culling & pitting of RBCs.
  16. 27. fat cells that maintain bone integreity , secrete steroids.
  17. 29. is hematopoietic precursor cells with progenitor and maturing cells.
  18. 30. IL-3,G-CSF, Cm-CSF priming bone marrow for
  19. 31. pleiotrophic act on multiple cell types & have multiple functions.
  20. 32. treatment of myelodysplastic disease
Down
  1. 1. process from commitment to the point where the cell has all of its characteristic.
  2. 2. recovery treatment after myelosuppression
  3. 3. cells for bone resorption.
  4. 4. are limited cells capacity for self-renewal , they have to commit to one cell line( Unipotential), mitotically more active than HSC, can be measure by CFu-GM,CFU-GEMM.
  5. 7. marrow are the primary site of hematopoiesis at 6 month.
  6. 9. mitotic cell division
  7. 13. stimulation of RBC production in kidney disease or other times of need.
  8. 15. phagocytes cells.
  9. 17. reticular fiber formation to support hematopoietic cells.
  10. 18. cells for bone formation.
  11. 19. region of the primary hematopoiesis variety of cells including lymphocytes.
  12. 21. stimulation of platelet production in thrombocytopenia.
  13. 28. prevents apoptosis, induce cell division , induce maturation , induce cell function.