HISTOLOGY & PATHOLOGY CROSSWORD PUZZLE

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Across
  1. 7. clearing agent used for tissues tend to become adulterated
  2. 10. refers to the complete non-appearance of an organ/ absence of an organ
  3. 13. process of tumor formation; characterized by continuous proliferation of abnormal cells
  4. 14. Alcohol fixative used for blood, tissue films and smears
  5. 15. procedure that it involves getting a tissue sample from a living person to identify the diagnosis
  6. 17. Can fix and dehydrate tissues at the same time; fix brain tissues for the diagnosis of rabies
  7. 19. Refers on the manner on how the disease had developed/sequence of events
  8. 20. refers to the failure of an organ to form an opening; a condition in which an orifice or passage in the body is either close
  9. 21. process of polishing and sharpening the cutting edge
  10. 22. due to increase dilatation of blood vessels resulting to an increase in the rate of blood flow in the site of injury
  11. 23. can act both as dehydrating and clearing agent; tissues tend to ribbon poorly
  12. 26. method of celloidin infiltration that uses 70% alcohol for storage ; for bones, brain, teeth, whole organs
  13. 27. routine clearing agent; becomes milky when an incompletely dehydrated tissue is immersed in it
  14. 28. Increase in tissue or organ size due to an increase in the size of individual cells comprising an organ
Down
  1. 1. This process make the bone easy for histopathological investigation by producing thin sections using a microtome
  2. 2. Pre-planned, regular process of cell death occurring in the body where the cell itself actively takes part in its own death
  3. 3. Regarded as the initial step; most important step in tissue processing
  4. 4. Fixative that is recommended for enzyme histochemistry and electron microscopy
  5. 5. the most rapid method (calcium is removed by electricity)
  6. 6. placing infiltrated tissue in a mold containing the embedding medium which is allowed to solidify
  7. 8. removal of dehydrating agent from tissues to replaced it with a medium that will dissolve the wax
  8. 9. Refers to acquired decrease in tissue or organ size
  9. 10. Automatic tissue processor that can do the first four steps (fixation, dehydration, clearing, infiltration) in tissue process
  10. 11. microtome knife that has 120mm long- both sides are concave and used to cut paraffin embedded tissues
  11. 12. a process in which water is entirely removed from the tissues
  12. 16. involves removal of clearing agent from tissues so that it will be replaced by a medium that will fill all cavities
  13. 18. the product of embedding, to be used in cutting
  14. 20. OIL clearing agent recommended for clearing embryos, insects and very delicate specimens
  15. 24. Due to the release of chemical substances like bradykinin that stimulates nerve endings for pain
  16. 25. highly flammable and carcinogenic clearing agent, can damage bone marrow leading to Aplastic Anemia