Across
- 2. T cells that modulate the immune response and limit chronic inflammatory diseases by recognizing antigen presented via MHC I or MHC II.
- 3. A specific immune response that develops when. Innate immunity cannot eliminate a pathogen is slower to develop, and can induce memory cells for future infections.
- 4. The key players of adaptive immunity that comprise 20–40% of all leukocytes, are the smallest type of white blood cell, and have a dark round nucleus with little cytoplasm.
- 5. The adaptive immune response mediated by B cells and antibodies that defends against infection in body fluids.
- 7. The process of obtaining immunity by inoculation with selected antigens, arts of a microbe, or in some cases the entire microbe to stimulate a primary and memory immune response.
- 12. Long-lived cells produced during an immune response that record information to fight a pathogen if it returns.
- 14. A Y-shaped protein molecule on B cells consisting of two identical heavy chains and two identical light chains with constant and variable regions that bind antigens.
- 15. T cells that recognize antigen presented via MHC II, express CD4, and activate other immune cells to fight pathogens.
Down
- 1. Cells such as macrophages, dendritic cells, and B cells that display antigen fragments on their surface via MHC molecules to activate T cells.
- 6. A substance that can elicit a response from a B or T cell.
- 8. A soluble form of the B cell receptor secreted by plasma cells that binds to pathogens and marks them for elimination.
- 9. A receptor on T cells consisting of two polypeptide chains (alpha and beta) with variable and constant regions that form antigen-binding site.
- 10. The small accessible part of an antigen that binds to an antigen receptor.
- 11. Activated B cells that actively secrete antibodies to defend against pathogens.
- 13. Immune cells produced and matured in red bone marrow that carry antibody receptors and are responsible for the humoral immune response.