Host Defenses II (BIO 202 Ch. 14)

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Across
  1. 3. Type of B cell that actively secretes antibodies
  2. 4. Edward Jenner coined this term in 1796 after injecting boy with one (material from human cowpox lesion) to make him immune to smallpox, from Latin for cow
  3. 7. Small accessible part of an antigen that binds to an antigen receptor
  4. 8. Type of T cell that modulates the immune response
  5. 10. Type of T cell, "conductor", detects pathogens and activates other immune cells to fight them
  6. 11. Type of B cell that "records" information to fight pathogen if it returns
  7. 12. Abbreviation for host proteins displaying antigen fragments on the cell surface
  8. 15. First recorded attempt was in sixth-century China, breathing in smallpox scab dust
Down
  1. 1. A B cell before BCR binds to an antigen
  2. 2. Any immunity obtained by inoculation with selected antigens/parts of a microbe (in some cases, entire microbe)
  3. 5. Substance that can elicit a response from a B or T cell
  4. 6. 20-40% of all leukocytes are this type, smallest type, dark round nucleus, little cytoplasm
  5. 9. 10th century inoculation of smallpox into healthy person's arm
  6. 13. Type of T cell that directly destroys cells it recognizes, presented by MHC I and express CD8
  7. 14. Soluble form of BCR that binds to pathogens and mark them for elimination