How Drugs Work

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Across
  1. 2. Processes the best course of action
  2. 3. Coordinates movement of muscles
  3. 6. A type of antagonist that binds to target and permanently prevents activation.
  4. 7. Diminished physiological or psychological effect after repeated use of the same drug.
  5. 9. A neurotransmitter that plays a central role in the reward system, often targeted by drugs of abuse.
  6. 10. Protect the axons so that neurons can send signals more efficiently
Down
  1. 1. A substrate that activates the target but does not produce the full response.
  2. 4. The mode of signal transmission via neurons in the central and peripheral nervous systems.
  3. 5. How a drug is chemically transformed in the body.
  4. 8. The dose of a drug that shows the therapeutic effect in 50% of test patients.