Across
- 2. The AI research institute co founded at the Vienna BioCenter in September 2024 to make artificial intelligence a partner in generating scientific hypotheses
- 4. The model organism maintained by a Vienna BioCenter Core Facility whose fly stocks support between 400 and 500 publications per year
- 7. IMP scientist whose lab builds new microscopes and develops the mathematical methods that allow individual molecules to be tracked inside living cells with nanometer precision
- 9. An early stage in the development of multicellular organisms that the Pinheiro lab recreates using stem cells, to study how the protective membrane surrounding it builds its distinct structure
- 11. IMP scientist whose lab designs rational drug combinations that target the specific vulnerabilities of cancer cells, with the goal of preventing tumors from adapting and developing resistance to treatment
- 13. IMP scientist whose lab discovered that the protein cohesin organizes the genome by reeling DNA into loops, a mechanism now recognized as fundamental across all kingdoms of life
- 17. The category of disease that can result from mutations in FOXP3, the master protein studied by the van der Veeken lab at the IMP that keeps the immune system from attacking the body’s own tissues
- 19. A disease causing organism whose DNA, when detected floating in the cell’s interior rather than safely stored in the nucleus, triggers a powerful immune alarm studied by the Gaidt lab at the IMP
- 20. One of the theatrical formats the Vienna BioCenter Amateur Dramatic Club has staged on campus since 2008, alongside rehearsed readings with visiting playwrights
- 21. Computational scientist who completed three collaborative publications during a one year visiting stay at the IMP in 2024, making machine learning tools accessible to experimental researchers
- 22. IMP scientist whose lab studies how cells mark unwanted proteins for destruction, with implications for developing new antibiotics and understanding muscle disease
- 23. Founding scientific director of the IMP, who recruited its first staff members and initiated the partnership with the University of Vienna that gave rise to the Vienna BioCenter
- 24. The skill that researchers develop through repeated setbacks, and is a facet of almost every scientific career
- 26. IMP scientist whose lab investigates how molecular machines package and export messenger RNA from the cell nucleus to the site of protein production
- 27. The platform launched in March 2025 by the Vienna BioCenter Scientific Training Unit that grew to nearly 1000 members within months, connecting former researchers with current students for career guidance
- 28. Biannual award for cancer research, won by IMP scientists in both 1988 Hartmut Beug and 2025 Anna Obenauf
- 30. Tissue whose proteins are studied by the Clausen lab at the IMP to understand how disease associated mutations lead to dysfunction and premature aging
- 31. The reversible pause in embryonic development used by species including killifish, bears, and marsupials to wait for better conditions, whose molecular mechanisms are studied by the Pauli lab at the IMP
- 33. IMP scientist who discovered that mammals, like plants and bacteria, use a sensing mechanism called Effector Triggered Immunity to detect and respond to the activities of invading pathogens
- 34. The number of research groups at the IMP in its 40th year, working across fields from genome organization to cancer research
- 36. The fundamental process by which a cell reads its DNA to produce RNA, whose control by enhancers and other regulatory sequences is decoded by the Stark lab at the IMP using a combination of experiments and artificial intelligence
Down
- 1. Visual design element created by algorithmically mirroring and tessellating microscopy images submitted by research groups at IMBA and the IMP
- 3. IMP scientist whose cryo electron microscopy technology platform studies how the proteasome adapts its structure to meet the cell’s changing needs
- 5. The TV soap opera that the IMP’s first generation of PhD students and postdocs watched together at five o’clock each day before returning to the labs two words
- 6. A particle formed by a group of atoms, held together by chemical bonds, which the Balzarotti lab aims to resolve microscopically, using DNA barcoding techniques that assign each target a unique code, allowing dozens of different species of such a particle to be mapped simultaneously at nanometer resolution
- 8. The approximate number of countries represented among the roughly 255 researchers at the IMP in 2025
- 10. The gene editing technology used by the Zuber lab at the IMP to run large scale screens that reveal which genes cancer cells depend on to survive
- 12. The molecular tag attached to damaged or unwanted proteins to mark them for recycling, whose chain structures and signals are studied by the Haselbach lab at the IMP
- 13. IMP scientist whose lab combined AI based protein structure prediction with experiments to identify the protein complex behind the first molecular contact between sperm and egg, described as the first kiss of life
- 14. IMP scientist whose lab engineers mouse models to study how regulatory T cells maintain immune balance, preventing the body from attacking its own healthy tissues three words
- 15. IMP scientist whose lab developed CaTCHseq, a platform that traces in real time how tumors develop resistance to treatment and how cancer cells learn to evade immune attack
- 16. Scientist at IMBA and the IMP, whose cryo electron tomography partnership with the Brennecke lab produced a landmark paper in the journal Cell in 2025
- 18. The international song contest, whose Vienna staging forced a complete rescheduling of a Vienna BioCenter scientific conference after every hotel room in the city was booked
- 22. The structure that packages DNA in the cell nucleus, whose abnormal organization when cohesin is defective can contribute to cancer and birth defects, according to research from the Peters lab at the IMP
- 24. Annual prize for early career researchers, established in memory of a former IMP PhD student
- 25. The compartment inside every cell that acts as a gatekeeper between the DNA blueprint and the protein making machinery, and whose molecular gates the Plaschka lab at the IMP studies by investigating how messenger RNA passes through them
- 26. IMP scientist who investigates the mechanical and chemical forces that drive cells to self organize into the right shapes during the earliest stages of embryonic development
- 28. IMP scientist whose lab developed DeepSTARR, a neural network that predicts how DNA sequences control gene activity, enabling the design of entirely synthetic enhancers
- 29. The ability of tumor cells to survive treatment by rewiring their signaling pathways and manipulating the immune system, and the central problem that the Obenauf lab at the IMP works to understand and overcome
- 32. The electronics company whose former factory in St. Marx was converted into the IMP’s first laboratory building in 1988
- 35. A gene that can copy and reinsert itself throughout the genome, posing a constant threat to genome stability that the Klumpe lab at the IMP investigates in fruit fly germline cells