computer simulation

3. interaction between two molecules that are not bonded
5. the qualitative property of a compound having the desired effect on a biological system
6. measure of pharmacokinetic and pharmacodynamic properties
8. A protein structure validation map
10. a method to assess the binding affinity between two molecules
13. It is measured in angstroms for protein structure
15. he set rules for drug likeliness
17. a zone of low sequence identity between target and the template
19. They get designed based on the gaps in the alignment
20. substituents or groups with similar physical or chemical properties which produce broadly similar biological properties to a chemical compound
21. This approach requires three-dimensional knowledge of the target structure
22. nonpeptide compound that has a similar shape and binding to the active site
23. A tool to perform homology modelling

1. A drug targeting ACE
2. use classical type models to predict the energy of a molecule as a function of its conformation
4. The three-dimensional geometry of interaction features that a molecule possesses
7. regulator of drug industry
8. placing of an asymmetric functional group in the molecule
9. historical method of discovering and developing drugs
11. A database for pathways
12. a famous receptor in the cells
14. double-stranded 20 - 25 nucleotides
16. you perform this assay if you know the target
18. Substrate and the inhibitor fight for the site