IMM Crossword

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Across
  1. 2. WBCs with multi lobed nuclei and cytoplasmic granules
  2. 3. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand
  3. 5. A type of APC involved in pathogen recognition and activation of immune responses.
  4. 7. antigen.
  5. 9. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
  6. 11. Not characterized as granulocytes but do have prominent granules
  7. 15. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  8. 17. Ab
  9. 20. Differentiate into macrophages
  10. 24. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  11. 25. protein family that Abs and B cells belong to
  12. 27. Large granulocyte involved in inducing apoptosis of target cells
  13. 28. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  14. 29. large agranulocyte that is phagocytotic; involved in innate immunity
Down
  1. 1. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  2. 2. Pathogen associated molecular patterns.
  3. 4. An Ig that is expressed on B cell surfaces
  4. 6. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  5. 7. A transcription factor that causes tissue specific genes to be transcribed.
  6. 8. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  7. 10. Adaptive immune responses in which there is a major role for effector T cells
  8. 12. the end stage of disease in HIV
  9. 13. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens
  10. 14. Have granules but aren't as prominent
  11. 16. Most prevalent granulocyte
  12. 18. The Ag receptor on T cells
  13. 19. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  14. 21. CD4 T cells involved in adaptive immunity
  15. 22. Family of cytokines that help cells to resist viral infection
  16. 23. A cell that is able to present Ag to T cell receptors on T cells.
  17. 26. immune response.