IMM Crossword

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Across
  1. 1. Pathogen associated molecular patterns.
  2. 3. A type of APC involved in pathogen recognition and activation of immune responses.
  3. 6. large agranulocyte that is phagocytotic; involved in innate immunity
  4. 9. immune response.
  5. 10. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  6. 12. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens
  7. 13. Ab
  8. 16. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand
  9. 18. Have granules but aren't as prominent
  10. 21. Not characterized as granulocytes but do have prominent granules
  11. 22. WBCs with multi lobed nuclei and cytoplasmic granules
  12. 24. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  13. 26. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  14. 28. Large granulocyte involved in inducing apoptosis of target cells
Down
  1. 2. A transcription factor that causes tissue specific genes to be transcribed.
  2. 4. Adaptive immune responses in which there is a major role for effector T cells
  3. 5. protein family that Abs and B cells belong to
  4. 7. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  5. 8. A cell that is able to present Ag to T cell receptors on T cells.
  6. 9. Family of cytokines that help cells to resist viral infection
  7. 11. Differentiate into macrophages
  8. 13. the end stage of disease in HIV
  9. 14. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  10. 15. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  11. 17. An Ig that is expressed on B cell surfaces
  12. 19. antigen.
  13. 20. CD4 T cells involved in adaptive immunity
  14. 23. Most prevalent granulocyte
  15. 24. The Ag receptor on T cells
  16. 25. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  17. 27. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells