IMM Crossword

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Across
  1. 2. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  2. 3. antigen.
  3. 5. Differentiate into macrophages
  4. 7. the end stage of disease in HIV
  5. 9. Adaptive immune responses in which there is a major role for effector T cells
  6. 10. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  7. 11. WBCs with multi lobed nuclei and cytoplasmic granules
  8. 13. protein family that Abs and B cells belong to
  9. 14. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  10. 15. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand
  11. 18. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  12. 19. Have granules but aren't as prominent
  13. 21. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  14. 22. An Ig that is expressed on B cell surfaces
  15. 23. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens
  16. 26. Pathogen associated molecular patterns.
  17. 27. A transcription factor that causes tissue specific genes to be transcribed.
Down
  1. 1. Large granulocyte involved in inducing apoptosis of target cells
  2. 2. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  3. 3. Ab
  4. 4. A type of APC involved in pathogen recognition and activation of immune responses.
  5. 5. large agranulocyte that is phagocytotic; involved in innate immunity
  6. 6. The Ag receptor on T cells
  7. 8. Family of cytokines that help cells to resist viral infection
  8. 12. Not characterized as granulocytes but do have prominent granules
  9. 13. immune response.
  10. 16. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  11. 17. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
  12. 20. Most prevalent granulocyte
  13. 24. CD4 T cells involved in adaptive immunity
  14. 25. A cell that is able to present Ag to T cell receptors on T cells.