IMM Crossword

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Across
  1. 5. large agranulocyte that is phagocytotic; involved in innate immunity
  2. 6. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
  3. 8. A transcription factor that causes tissue specific genes to be transcribed.
  4. 13. Have granules but aren't as prominent
  5. 15. Adaptive immune responses in which there is a major role for effector T cells
  6. 17. differentiate from CD8 T cells (cytotoxic t lymphocytes)
  7. 19. Subset of CD4+ T cells characterized by the cytokines they produce; involved in stimulating B cells to produce antibody against extracellular pathogens
  8. 22. Differentiate into macrophages
  9. 27. Most prevalent granulocyte
  10. 28. slg on B cells that binds Ag and transmits signal 1 to activate B cells
  11. 30. Autoimmune disease where autoantibodies (against DNA, RNA and proteins associated with nucleic acids) form immune complexes
  12. 31. the end stage of disease in HIV
Down
  1. 1. The Ag receptor on T cells
  2. 2. Not characterized as granulocytes but do have prominent granules
  3. 3. Designation for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
  4. 4. antigen.
  5. 7. Large granulocyte involved in inducing apoptosis of target cells
  6. 9. Family of cytokines that help cells to resist viral infection
  7. 10. Pathogen associated molecular patterns.
  8. 11. immune response.
  9. 12. A type of APC involved in pathogen recognition and activation of immune responses.
  10. 14. A cell that is able to present Ag to T cell receptors on T cells.
  11. 16. protein family that Abs and B cells belong to
  12. 18. Subset of CD4+ T cells characterized by the cytokines they produce; involved in fully activating macrophages and promoting CTL responses against intracellular pathogens
  13. 20. WBCs with multi lobed nuclei and cytoplasmic granules
  14. 21. Ab
  15. 23. Subset of CD4 T cells that is responsible for suppressing/limiting immune responses
  16. 24. receptors on immune cells and epithelial cells that recognize and bind PAMPs
  17. 25. CD4 T cells involved in adaptive immunity
  18. 26. An Ig that is expressed on B cell surfaces
  19. 29. Member of TNF receptor family expressed on some cells making them susceptible to being killed by cells expressing the Fas ligand