Immune control and Immunopathology of SARS-CoV-2

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Across
  1. 4. Immune cell subset specialized in antigen-presentation during adaptive immune responses (two words)
  2. 7. Virus-infected cells are detected and killed by CD8+ ... T cells.
  3. 11. Crucial components of the ... immune system are myeloid cells and the complement system.
  4. 14. Virus ... is the major contribution of antibodies in immune defense
  5. 16. Immunologic ... is a specific feature of the adaptive immune response.
  6. 17. cytokines with chemoattractant function
  7. 19. Innate immune cells first recruited to the site of infection
  8. 21. Inflammatory mediators responsible for cell-cell communication within the immune system
  9. 22. type I ... are produced by epithelial cells upon recognition of viral infection
  10. 23. storm Severe complication of SARS-CoV-2 infection due to systemic release of proinflammatory mediators (two words)
Down
  1. 1. ACE2 cleaves ... II
  2. 2. Differentiated B cell subsets specialized in antibody production
  3. 3. ... describes a potentially enhanced infectious capacity in presence of neutralizing antibodies
  4. 5. pathologic consequence of platelet activation
  5. 6. pathway SARS-CoV-2 can activate the ... the pathway of complement system
  6. 8. soluble effector molecules of the adaptive/humoral immune response
  7. 9. The ultimate goal of the immune response is ... of infection.
  8. 10. Reduced ACE2 expression in the circulatory system including heart and kidney results in ...
  9. 12. Clearance of antibody- or complement opsonized virus is accomplished via ...
  10. 13. viral surface protein responsible for target cell infection (two words)
  11. 15. Severe complication of infection of lung epithelium
  12. 18. The viral genome is composed of ...
  13. 20. ... molecules present viral peptides to immune cells.