Across
- 2. When WBCs are attracted to an area by chemical factors like complement fragments or cytokines.
- 4. Fixed and wandering monocytes in tissues, performing phagocytosis and antigen presentation.
- 5. Stem cells that can differentiate into every blood cell type, comprising about 0.01% of all bone marrow cells.
- 8. The development of blood cells, occurring almost entirely in the bone marrow in adults.
- 11. Granulocytes associated with parasitic infections and allergic reactions, and are weak phagocytes.
- 13. Granulocytes that are the most numerous WBC in peripheral blood (~65%) and are very phagocytic.
- 16. Specific immunity referring to antibody production by B lymphocytes.
- 19. Type of immunity that is dormant until a stimulus is encountered and has memory.
- 22. an older term for MHC antigens first identified on WBCs.
- 23. The redness characteristic of inflammation (also known as rubor).
- 24. Hormone produced by the thymus that promotes T cell function and differentiation.
- 27. Enhancement of phagocytosis by coating a particle with factors such as antibodies, complement fragments, or CRP.
- 29. The variation present in the variable region of an immunoglobulin.
- 30. Term for cellular products secreted to have an effect on other cells; chemical messengers of the immune system.
- 34. When WBCs squeeze through epithelial membranes/vessel walls into a site of inflammation.
- 35. Any substance that is the specific target of an immune response.
Down
- 1. Granulocytes that contain histamine and vasoactive molecules, associated with allergy and inflammation.
- 2. Specific immunity mediated by T lymphocytes, effective against viruses, fungi, protozoa, and tumors.
- 3. Any substance capable of producing an immune response.
- 6. Primary lymphoid organ where T cells are educated and complete their maturation.
- 7. A severe systemic inflammation that can be life-threatening.
- 9. The swelling characteristic of inflammation (also known as turgor).
- 10. Strength of an antibody solution expressed as a dilution factor.
- 12. process and display antigens to T cells (e.g., macrophages, dendritic cells).
- 14. Generalized response to injury or infection characterized by edema, heat, pain, and erythema.
- 15. genes found on chromosome 6 that help lymphocytes discriminate "self" from "non-self".
- 17. A substance that initiates an allergic immune response.
- 18. The study of mechanisms that protect organisms from injury
- 20. B cells differentiated to produce large amounts of antibody, also called antibody factories.
- 21. Process where a cell actively engulfs, ingests, and digests particulate matter.
- 25. A small substance that is not immunogenic unless attached to a carrier molecule.
- 26. Antibody variation due to heavy and light chains, defining the class (e.g., IgG, IgM, IgA).
- 28. The combined strength of all antibodies in a polyclonal mixture for an antigen.
- 31. Type of immunity present from birth that does not depend on previous stimulation and lacks memory
- 32. The exact portion of an antigen that is recognized by the immune response.
- 33. Agents that enhance the ability of the immune system to react, but are not immunogenic themselves.