Immune System

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Across
  1. 2. The actual protection from foreign microorganisms or antigenic substances is known as the body's _____.
  2. 4. _____ immunity involves a learned immune response due to previous exposure to a specific antigen.
  3. 6. When white blood cells migrate to the site of inflammation or injury in response to chemical messengers, it is known as _____.
  4. 8. _____ T-cells release chemicals that kill infected cells.
  5. 9. ___ is the immunoglobulin associated with secretory, mucosal tissues and is found in high concentrations in mammary secretions.
  6. 11. A great example of artificially acquired immunity that can produce immunologic memory is _____.
  7. 12. These proteins are produced by B-cells and can bind to a specific antigen, identifying it as invasive.
  8. 13. A B-cell can be activated by _____ T-cells through cytokine release.
  9. 15. When antibodies coat an antigen and mark it for phagocytosis, it is called _____.
  10. 16. ___ is the predominantly circulating immunoglobulin.
  11. 18. Adaptive immune defenses exhibit _____, meaning if an antigen is encountered multiple times, the immune response will immediately recognize and defend against it.
  12. 19. When a cell is invaded by a virus, it produces _____ which signals neighboring cells to increase protection, signal infected cells to die, and stimulate leukocyte activity.
  13. 20. Innate immune defenses are _____, meaning they attack any antigenic material identified as non-self.
  14. 23. Interferons can stop viruses from _____ if they have entered and newly infected a cell.
  15. 24. A _____ is a cell that is responsible for engulfing and digesting pathogens.
  16. 25. Lymphocytes that are part of the innate immune system and kill cells infected with viruses with cytotoxic granules are called _____ _____ cells. (2 words)
  17. 26. T lymphocytes mature in the _____.
  18. 27. This type of adaptive immunity involved the production of antibodies in response to the encounter of a specific antigen.
  19. 29. The secretion of immunoglobulins into colostrum and their ingestion by the neonate is an example of what type of acquired immunity?
  20. 30. _____ occurs when a pathogen bypasses an external barrier and causes edema, redness, and heat.
  21. 31. _____ can either be circulating or present within the cell membrane of B lymphocytes.
Down
  1. 1. B lymphocytes mature in the _____ _____. (2 words)
  2. 3. Lymphocytes and monocytes are examples of _____, which are leukocytes that do not contain granules.
  3. 5. _____ cells are macrophages present in the skin that can act as antigen-presenting cells after phagocytizing a pathogen.
  4. 7. Leukocytes are produced through the process of _____ from lymphoid stem cells.
  5. 9. ___ is the least prevalent immunoglobulin and can activate B cell activity along with IgM.
  6. 10. _____ immunity includes components like the skin and its secretions and inflammation or fever.
  7. 14. The organelle containing digestive and degradative enzymes that accomplishes pathogen destruction in phagocytes is called a(n) _____.
  8. 16. ___ is the immunoglobulin associated with allergic responses.
  9. 17. Eosinophils, neutrophils, and basophils are examples of _____, which are a type of leukocyte containing small secretory particles in the cytoplasm.
  10. 19. ___ is the largest immunoglobulin and is produced first when the body encounters a new antigen.
  11. 21. This type of adaptive immunity is typically associated with lymphocytes that kill pathogens or infected cells.
  12. 22. When an immune cell communicates with other cells during an immune response, what chemicals are released?
  13. 28. A(n) _____ is a molecule that can activate an immune response targeting itself.