Across
- 4. an agent that causes disease in the organisms that it invades
- 7. destructive protein that creates a pore in the target cell and is used by NK cells and killer T cells
- 8. attraction of molecular complementarity between antigen and antibody molecules
- 9. leukocyte that responds to parasites and is involved in the allergic response
- 10. type of white blood cell that circulates in the blood and lymph and differentiates into macrophages after it moves into infected tissue
- 12. leukocyte that produces inflammatory molecules in response to large pathogens and allergens
- 13. a type of immunity that has memory
- 16. immunity that occurs naturally because of genetic factors or physiology and is not induced by infection or vaccination
- 19. spectrum of maladaptive immune responses toward harmless foreign particles or self antigens; occurs after tissue sensitization and includes immediate-type (allergy)-delayed-type- and autoimmunity
- 24. watery fluid that bathes tissues and organs with protective white blood cells and does not contain erythrocytes
- 25. protein that is produced by plasma cells after stimulation by an antigen; also known as an immunoglobulin
- 26. failure or insufficiency or delay at any level of the immune system that may be acquired or inherited
- 29. protease that enters target cells through perforin and induces apoptosis in the target cells
- 30. chemical messenger that regulates cell differentiation-proliferation-gene expression and cell trafficking to effect immune responses
- 31. antibody that incorrectly marks “self” components as foreign and stimulates the immune response
- 32. an organism that is invaded by a pathogen or parasite
Down
- 1. phagocytic leukocyte that engulfs and digests pathogens
- 2. immune cell that processes antigen material and presents it on the surface of other cells to induce an immune response
- 3. small component of an antigen that is specifically recognized by antibodies, B cells, and T cells
- 5. localized redness or swelling or heat and pain that results from the movement of leukocytes and fluid through opened capillaries to a site of infection
- 6. immune reaction that results from immediate hypersensitivities in which an antibody-mediated immune response occurs within minutes of exposure to a harmless antigen
- 11. process that enhances phagocytosis using proteins to indicate the presence of a pathogen to phagocytic cells
- 14. type of hypersensitivity to self antigens
- 15. antigen-specific B or T lymphocyte cell that does not differentiate into effector cells during the primary immune response but that can immediately become an effector cell upon re-exposure to the same pathogen,
- 17. cytokine that inhibits viral replication and modulates the immune response
- 18. leukocyte that releases chemicals usually involved in the inflammatory response
- 20. an immune cell that secrets antibodies; these cells arise from B cells that were stimulated by antigens
- 21. immunity that arises from the transfer of antibodies from one individual to another to provide temporary protection against pathogens
- 22. leukocyte that is histologically identifiable by its large nuclei and small cell size with very little cytoplasm
- 23. foreign or “non-self” protein that triggers the immune response
- 27. large phagocytic cell that engulfs foreign particles and pathogens
- 28. total binding strength of a multivalent antibody with antigen