Immune System Crossword

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Across
  1. 2. This occurs when mast cells release compounds to dilate blood vessels.
  2. 4. Large phagocytes that develop from monocytes. These are slower to respond to an infection but stay on the site longer.
  3. 6. Type of cytokine that acts as a signaling molecule. They attract, activate, and direct the movement of different immune cells.
  4. 7. Common clinical symptom of wide spread inflammation. Hypothalamus increases body temperature in order to help prevent pathogens from replicating. Also promotes the activity of certain lymphocytes.
  5. 8. Type of cytokine that responds to infections by viruses or other intracellular parasites. Type one inhibits viral replication and activates NK cells. Type two stimulates macrophages to destroy tumor cells and host cells that are infected by a virus.
  6. 10. Type of cell that is responsible for antibody-mediated immunity. Matures into plasma cells which creates specific antibodies.
  7. 11. The most common white blood cell that responds quickly to an infection but also quickly "loses interest" in it.
  8. 14. Type of cell responsible for cell-mediated immunity. Attacks body cells infected by pathogens, foreign cells, or cells altered by mutations.
  9. 17. This type of cell is a large, granular lymphocyte that use perforins to form pores in target cells. They destroy targets by nonspecific and specific (antibody-mediated) processes.
  10. 18. Type of immunity where the immune system recognizes specific molecules as foreign.
  11. 19. A large and diverse group of peptides and proteins that signal molecules as well as regulate the immune response. They are produced by a wide variety of cells.
Down
  1. 1. Type of immunity that provides an immediate, general protection against pathogens, parasites, some toxins and drugs, and cancer cells.
  2. 3. Type of cytokine that stimulates immune cells to initiate an inflammatory response. It also acts on the hypothalamus to induce fever. A large release of this can lead to septic shock.
  3. 5. This type of cell develops from monocytes and has long extensions of the cytoplasm. They capture microbial antigens by phagocytosis or receptor-mediated endocytosis.
  4. 9. This type of immune system response involves vasodilation, increased capillary permeability, and increased phagocytosis.
  5. 12. Compound secreted by mast cells which increase capillary permeability.
  6. 13. Type of cytokine that affects the cell that produced it.
  7. 15. Study of internal defense systems of humans and other animals.
  8. 16. Type of cytokine that regulates the activities of nearby cells. They only last a short amount of time.
  9. 19. This type of protein involves a cascade of reactions. They work to destroy pathogens by creating pores in pathogens, coating pathogens so macrophages can phagocytose them easier, attract white blood cells to the infection site, and bind to receptors on immune system cells to stimulate them.
  10. 20. Type of cytokine that is mainly secreted by macrophages and lymphocytes. They work to regulate interactions between white blood cells and other cells. Type one works with TNF to mediate inflammation. Type twelve stimulates NK cells and T cells to produce INF-gamma.