Across
- 2. This is known as the complete set of sequences in the genetic material of an organism.
- 5. These types of cells are lymphocytes of the innate immunity that defend against viral infections by secreting cytokines and killing infected cells?
- 6. The ______ peptide directs the protein into the cell's secretory pathways and is then cleaved.
- 7. This describes an antigen that contains more than one epitope, or more than one copy of the same epitope.
- 9. What complex initiates a cascade of reactions enabling the next reaction in the sequence in the classical pathway?
- 11. These types of cells are short-lived activated cells that defend the body in an immune response.
- 13. What chain guides transport of class II MHC molecules to endocytic vesicles?
- 15. Antibody structure consists of a quaternary protein with two identical heavy chains (H) and what other two identical chains?
- 16. The physical location of a gene on a chromosome
- 18. The total number of antibody specificities available to an individual is known as antibody ________.
- 19. What is the movement of leukocytes out of the blood vessel to the infected tissue?
Down
- 1. The cell-surface B-cell antigen receptors and the secreted antibodies are known more generally as what?
- 3. These types of antibodies are produced from a clone of the antibody-producing b-cells.
- 4. What can bind in pockets, or grooves, or on extended surfaces in the binding sites of antibodies?
- 8. What immunity involves both humoral and cellular components?
- 9. What molecules mediate isotope switching?
- 10. This type of hypermutation occurs in mature B cells, acting only on rearranged DNA encoding the V regions.
- 12. This is the part of a pathogen to which an antibody binds.
- 14. The different forms of any given gene are called alleles, what are their encoded proteins are called?
- 17. What is the coating of the pathogen with a protein that facilitates Phagocytosis?