Immunity and Cancer

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Across
  1. 3. Derived from epithelial cells like skin, mucous membranes, linin, and viscera coverings. Most common type of malignancy.
  2. 4. _____ rejection reaction occurs in 10 days to few months after the transplant. Involves cellular and T-lymphocyte proliferation. Results in organ failure and inflammation of blood vessels.
  3. 7. _____ immunity bolsters the immune system by inducing antibody formation using dead or weakened microorganism or piece of microorganism. Tend to provide life-long immunity.
  4. 11. _____ refers to evaluation of cancer severity based on the tissue involvement.
  5. 12. _____ rejection includes complement activation, endothelial damage, inflammation, and thrombosis of the transplanted kidney. Reduced incidence due to careful screening of transplant donors and recipients.
  6. 14. refers to all malignant cells are killed or reduced to a small amount that can be killed by the immune system.
  7. 15. Refers to uncontrolled growth without regard to growth regulation signals like contact with other cells.
  8. 16. _____ refers to a cytokine that contributes to prolonged tissue inflammation and damage. It is attributed to certain autoimmune conditions like psoriasis and Crohn’s disease.
Down
  1. 1. ______ refers to cancer evaluation based on the degree of malignancy. It rates tissues that are unlike the tissue of origin (less differentiated) as more malignant.
  2. 2. AKA CellCept IV. Prodrug. Interferes with the production of cell DNA and RNA and blocks cell reproduction, growth, and development.
  3. 5. Drug of choice for anemia associated with chemotherapy.
  4. 6. Preferred drug over cyclosporine because it does not require steroid use. Causes serious infection associated with lifelong immune suppression therapy as well as risk for malignancy like skin and lymphoma.
  5. 8. _____ results from exposure of protooncogenes to carcinogens.
  6. 9. Buildup of extra cells that change the tissue organization.
  7. 10. Drug of choice for nausea and vomiting associated with cancer cytotoxic therapy. It is most effective when started prior to cancer drug administration.
  8. 13. _____ immunity provides immune serum that is disease or organism-specific. Temporary immunity.