Immunology

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Across
  1. 3. multiple drug treatment for HIV infection
  2. 5. transcription factor that helps activate the expression of pro-inflammatory genes
  3. 7. cell adhesion molecule
  4. 8. end product of complement cascade that can kill pathogens directly by forming a pore in the pathogen membrane leading to lysis
  5. 12. cytokines that help cells resist viral infections
  6. 14. differentiate into T helper phenotypes with roles in adaptive immunity
  7. 15. immune response
  8. 16. adaptive immune responses in which there is a major role for effector T cells
  9. 18. WBCs with multilobed nuclei and cytoplasmic granules
  10. 20. a transcription factor that causes several hundred tissue specific genes to be transcribed by epithelial cells in the thymus
  11. 22. NK cells use this mechanism to induce apoptosis in virally infected cells
  12. 23. differentiate into cytotoxic T cells
  13. 25. immunoglobulin that is expressed on B cell surface
  14. 26. end stage disease of HIV
  15. 28. cytokine that is a chemical messenger secreted by immune cells that help in their communication with other cells
Down
  1. 1. cytokine produced by macrophages and T cells that is highly pro-inflammatory
  2. 2. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
  3. 3. name of MHC gene complex and proteins in humans
  4. 4. a molecule recognized in native structure by antibodies
  5. 6. can differentiate into plasma cells
  6. 9. adaptive immune responses in which there is a major role for effector cells
  7. 10. specific cell surface molecules on immune cells that help to differentiate immune cells
  8. 11. chemokines
  9. 13. lymphocyte that induces apoptosis of target cells
  10. 14. acute phase protein that binds to phosphocholine
  11. 17. intracellular adhesion molecules
  12. 19. cell surface molecules involved in presentation of peptide antigens
  13. 20. cell that is able to present antigen via MHC molecules to T cell receptors
  14. 21. thymus derived lymphocyte comprised of CD4 and CD8 cells
  15. 24. cell wall component of gram negative bacteria
  16. 26. immunoglobulin secreted by plasma cells
  17. 27. presents antigen of MHC to T cells
  18. 28. protein family to which antibodies and B cell receptors belong