Across
- 2. CD4+ T cells that assist in immune responses by activating other immune cells.
- 5. Protein molecule found on cytotoxic T cells that binds to MHC class I molecules and plays a role in the immune response.
- 8. Cell surface proteins that present antigens to helper T cells (CD4+) for immune response activation.
- 11. Selection Process in the thymus where T cells that strongly react against self-antigens are eliminated.
- 13. Signals required for full activation of T cells upon antigen recognition, providing secondary activation signals.
- 14. Protein molecule found on helper T cells that binds to MHC class II molecules and plays a role in the immune response.
- 15. Process in the thymus where T cells that recognize self-MHC molecules survive.
- 16. Cells that process and present antigens to T cells. Examples include dendritic cells (DCs), macrophages, and B cells.
Down
- 1. Lymphoid tissue in the small intestine that plays a role in mucosal immunity.
- 3. Organ where T cells mature and undergo positive and negative selection.
- 4. Intracellular vesicles involved in the processing of exogenous antigens for presentation by MHC class II molecules.
- 5. Signaling proteins that regulate cell migration and are involved in immune cell attraction to specific sites.
- 6. Node Small, bean-shaped organs where immune cells gather to facilitate immune responses and filter lymph.
- 7. A type of APC that plays a critical role in initiating immune responses by presenting antigens to T cells.
- 9. Cell surface proteins that present antigens to cytotoxic T cells (CD8+) for immune response activation.
- 10. Mechanism by which the immune system does not attack the body's own cells.
- 12. (Natural Regulatory T Cells): Subset of T cells that suppress excessive immune responses and maintain self-tolerance.
