Immunology 2

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Across
  1. 2. CD4+ T cells that assist in immune responses by activating other immune cells.
  2. 5. Protein molecule found on cytotoxic T cells that binds to MHC class I molecules and plays a role in the immune response.
  3. 8. Cell surface proteins that present antigens to helper T cells (CD4+) for immune response activation.
  4. 11. Selection Process in the thymus where T cells that strongly react against self-antigens are eliminated.
  5. 13. Signals required for full activation of T cells upon antigen recognition, providing secondary activation signals.
  6. 14. Protein molecule found on helper T cells that binds to MHC class II molecules and plays a role in the immune response.
  7. 15. Process in the thymus where T cells that recognize self-MHC molecules survive.
  8. 16. Cells that process and present antigens to T cells. Examples include dendritic cells (DCs), macrophages, and B cells.
Down
  1. 1. Lymphoid tissue in the small intestine that plays a role in mucosal immunity.
  2. 3. Organ where T cells mature and undergo positive and negative selection.
  3. 4. Intracellular vesicles involved in the processing of exogenous antigens for presentation by MHC class II molecules.
  4. 5. Signaling proteins that regulate cell migration and are involved in immune cell attraction to specific sites.
  5. 6. Node Small, bean-shaped organs where immune cells gather to facilitate immune responses and filter lymph.
  6. 7. A type of APC that plays a critical role in initiating immune responses by presenting antigens to T cells.
  7. 9. Cell surface proteins that present antigens to cytotoxic T cells (CD8+) for immune response activation.
  8. 10. Mechanism by which the immune system does not attack the body's own cells.
  9. 12. (Natural Regulatory T Cells): Subset of T cells that suppress excessive immune responses and maintain self-tolerance.