Immunology

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Across
  1. 3. Type of antibody grown from a single cloned hybridoma
  2. 7. The condition typically characterized by a defective thymus and a lack of mature T cells
  3. 9. Origination and development of a disease
  4. 11. is generated by V(D)J recombination, junctions diversity, and somatic hypermutation
  5. 12. The shrinking of the the thymus with age
  6. 14. Name of the type of cell that ingests immature T-cells that undergo apoptosis.
  7. 15. Infectious organism that causes disease
  8. 16. What type of cell is not marked by CD4 or CD8 surface marker molecules?
  9. 18. Proteins that display antigens from extra cellular pathogens
  10. 19. Embedded in an network of epithelial cells
  11. 20. T cells specific for self antigens are removed in the thymus by
Down
  1. 1. Production of diversity in the antigen-binding sites of immunoglobulins
  2. 2. The state of protection against foreign pathogens or substances
  3. 4. what type of T cell selection takes place in the cortex of the thymus?
  4. 5. Dedicated to T-cell development and contains immature T cells.
  5. 6. What type of cell is marked by both CD4 and CD8 surface marker molecules?
  6. 8. consist of immature thymocytes, branched cortical epithelial cells, and few macrophages.
  7. 10. Located in the thymus has numerous lobes, each has a less dense inner region.
  8. 13. Proteins that display antigens from intracellular pathogen
  9. 17. Dendritic cells in the skin and other peripheral tissues