Immunology

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Across
  1. 2. Activated by antigen presented on MHC II CD4+
  2. 8. Regulates development, effector function, and homeostasis of cells of the skeletal, neuronal and immune systems
  3. 9. Phagocytes and granulocytes
  4. 11. Recognizing non self in innate immunity
  5. 13. Happens in bone marrow during development
  6. 14. Relatively rare circulating granulocyte that fights parasitic infections
  7. 18. Lymphoid that does not recognize antigens
  8. 20. Takes antigens from periphery and presents them to lymph nodes to activate adaptive immune response
  9. 22. Activated by recognizing antigen CD40+
  10. 24. Primary: Bone marrow and Thymus, Secondary: Spleen and lymph nodes
  11. 25. Granulocyte found in tissues especially epithelia
  12. 27. Terminally differentiated
Down
  1. 1. Circulating precursor to phagocytic cells
  2. 3. Circulating granulocyte that fights parasitic infections and contributes to asthma and other allergies
  3. 4. T-cells and B-cells
  4. 5. Becomes faster and stronger with each new exposure
  5. 6. Has Fc region with a flexible hinge
  6. 7. Basophils, mast cells, natural killer cells
  7. 10. Cells that directly recognize antigens
  8. 12. Short lived phagocyte that is recruited to the site of infection
  9. 15. Monocytes, neutrophils, dendritic cells, macrophages
  10. 16. Recognizing non self in adaptive immunity
  11. 17. Antigen presenting cell that can be activated by T cells and antibody binding
  12. 19. Often stimulate cell proliferation and/or differentiation of blood cells
  13. 21. Kills cells presenting antigens on MHC I via its TCR CD8+
  14. 23. Same response every time
  15. 26. Produced by a lot of cells in response to PAMPs, promotes inflammation