Across
- 2. Activated by antigen presented on MHC II CD4+
- 8. Regulates development, effector function, and homeostasis of cells of the skeletal, neuronal and immune systems
- 9. Phagocytes and granulocytes
- 11. Recognizing non self in innate immunity
- 13. Happens in bone marrow during development
- 14. Relatively rare circulating granulocyte that fights parasitic infections
- 18. Lymphoid that does not recognize antigens
- 20. Takes antigens from periphery and presents them to lymph nodes to activate adaptive immune response
- 22. Activated by recognizing antigen CD40+
- 24. Primary: Bone marrow and Thymus, Secondary: Spleen and lymph nodes
- 25. Granulocyte found in tissues especially epithelia
- 27. Terminally differentiated
Down
- 1. Circulating precursor to phagocytic cells
- 3. Circulating granulocyte that fights parasitic infections and contributes to asthma and other allergies
- 4. T-cells and B-cells
- 5. Becomes faster and stronger with each new exposure
- 6. Has Fc region with a flexible hinge
- 7. Basophils, mast cells, natural killer cells
- 10. Cells that directly recognize antigens
- 12. Short lived phagocyte that is recruited to the site of infection
- 15. Monocytes, neutrophils, dendritic cells, macrophages
- 16. Recognizing non self in adaptive immunity
- 17. Antigen presenting cell that can be activated by T cells and antibody binding
- 19. Often stimulate cell proliferation and/or differentiation of blood cells
- 21. Kills cells presenting antigens on MHC I via its TCR CD8+
- 23. Same response every time
- 26. Produced by a lot of cells in response to PAMPs, promotes inflammation
