Immunology

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Across
  1. 5. Ability to respond faster and stronger upon re-exposure to antigen
  2. 11. Protective lining that blocks microbes at body surfaces
  3. 14. Chemical molecules that directly inhibit microbial growth
  4. 15. Professional antigen-presenting cell linking innate and adaptive immunity
  5. 18. Generation of long-lived memory lymphocytes
  6. 22. Primary lymphoid organ where hematopoiesis occurs and B cells mature
  7. 23. Protein cascade that enhances pathogen elimination
  8. 25. Uptake of pathogen-derived antigens by dendritic cells
  9. 31. Receptor that recognizes conserved microbial and danger patterns
  10. 32. Innate lymphocyte that kills virus-infected and tumor cells
  11. 33. Normal microbial community that competes with pathogens
  12. 34. Secondary lymphoid organs that monitor tissue-draining lymph
  13. 37. Initial step in which microbes enter host tissues
  14. 39. Mechanical expulsion of microbes and irritants from respiratory tract
  15. 41. Physical barrier that prevents pathogen entry
  16. 42. Lymphoid structures in the gut that sample intestinal antigens
  17. 43. Rapid nonspecific defense with no immunologic memory
  18. 46. Coordinated response involving vascular and cellular changes after injury or infection
  19. 47. Antibody-secreting effector B cell
  20. 50. Antigen-specific defense that develops memory
Down
  1. 1. Immune action that eliminates pathogens
  2. 2. Detection of microbes by resident innate immune cells
  3. 3. Signaling molecules that attract immune cells
  4. 4. Faster and stronger response after repeat antigen exposure
  5. 6. Pathogen-associated molecular pattern recognized by innate receptors
  6. 7. Mucosa-associated lymphoid tissue involved in mucosal immunity
  7. 8. Adaptive immune cell responsible for cell-mediated immunity and regulation
  8. 9. Protection provided by commensals through competition for space and nutrients
  9. 10. Secondary lymphoid organ that filters blood-borne antigens
  10. 12. Movement of dendritic cells to draining lymph nodes
  11. 13. Mechanical defense that removes pathogens from airways
  12. 16. Primary lymphoid organ where T cells mature
  13. 17. Early innate responder specialized for bacterial phagocytosis
  14. 19. Production of blood and immune cells
  15. 20. Primary role of immunity to defend against pathogens
  16. 21. Adaptive immune cell that differentiates into plasma and memory cells
  17. 24. Protective secretion that traps microbes at mucosal surfaces
  18. 26. Signaling proteins that regulate immune responses
  19. 27. Initial immune response that is slower and less robust
  20. 28. Activation of antigen-specific T and B lymphocytes
  21. 29. Multi-layered defense system that protects the host while minimizing self-damage
  22. 30. Damage-associated molecular pattern released from injured cells
  23. 35. Breakdown of antigens into peptides for presentation
  24. 36. Mechanical movement that helps remove pathogens from the gastrointestinal tract
  25. 38. Tissue-resident cells that continuously monitor for danger
  26. 40. Display of processed peptides on MHC molecules to T cells
  27. 44. Microbe-associated molecular pattern recognized by PRRs
  28. 45. Phagocytic sentinel cell that produces cytokines and cleans tissues
  29. 48. Enzyme that damages bacterial cell walls
  30. 49. Potential harmful consequence of immune responses causing tissue damage