Across
- 2. APC that presents Ag in the context of MHC to T cells
- 3. Repeating molecular patterns on microbes
- 6. Key transcription factor required to bind to IL-2
- 8. Part of Ab responsible for Ag binding
- 9. Family of cytokines that cells resist viral infections
- 11. End product of Complement cascade that kills pathogens
- 13. Soluble protein that binds to mannose on pathogens
- 14. Transcription factor expressed by Treg cells
- 15. Region of Ab where Fc receptors bind
- 17. TNF receptor on cells increasing susceptibility to death by cells with Fas ligand
- 18. Adaptive IR where effector T cells play a major role
- 19. Multiple drug treatment for HIV infection
- 21. AA sequence involved in signal transduction
- 23. Molecule recognized by Ab or BCR or peptide presented by MHC to TCR
- 24. protein that binds to phosphocholine on bacteria
- 25. CD8+ T cells with effector function
- 27. Ag receptor on T cells
- 28. Cell surface molecules that present peptide Ag to T cells
- 30. Receptors that recognize and bind to PAMP's
- 31. Regions of Ag binding loops of Ig molecules
- 32. Ig secreted by plasma cells
- 34. cells, Activates macrophages and promotes CTL responses
- 35. Short DNA sequences flanking Ig and TCR (V,D & J) gene segments
- 37. Family of PRR that recognize PAMPs
- 38. T cell subset responsible for suppressing or limiting IR
Down
- 1. Receptors that bind to Fc portion of IgG molecules
- 4. WBC with multi-lobed nuclei and cytoplasmic granules
- 5. Cell surface ligands for leukocyte integrins
- 7. Cytokine produced by mPhi and T cells
- 8. Part of Ab
- 9. General designation of cytokines and chemical messengers secreted by immune cells
- 10. Chemokine receptor family of G-protein-coupled transmembrane receptors
- 12. Transcription factor that activates expression of pro-inflammatory genes
- 16. cell, Large granular lymphocyte; innate effector
- 20. Mechanism NK cells use to induce apoptosis
- 21. Protein family of antibodies and B-cell receptors
- 22. Ig expressed on B cell surface
- 23. Transcription factor causing gene transcription in the thymus
- 24. cell-surface molecules that help differentiate immune cells
- 26. Cell wall component of gram negative bacteria
- 29. MHC gene complex and proteins in humans
- 31. Chemokine family of cell-attracted cytokines
- 33. slg on B cells that binds Ag and transmits signal 1 to activate B cells.
- 36. Autoimmune disease
- 38. cells, Stimulates B cells to produce Ab against pathogens
