Across
- 1. lymphoid tissues along the mucosa membrane
- 5. a large mononuclear phagocyte that takes residence in many different tissues and organs and contributes to innate immune responses and can act as an effector cell in adaptive immune responses
- 7. a disease where autoantibodies form immune complexes
- 8. T cells that express the co-receptor protein CD4 which upon activation differentiate into distinct Thelper phenotypes with different roles in adaptive immunity
- 9. Member of TNF receptor family expressed on certain cells that makes them susceptible to being killed by cells expressing the Fas ligand
- 11. an acute phase protein that binds to phosphocholine that can trigger Complement activation and acts as an opsonin
- 15. designated for a family of cell surface molecules involved in the presentation of peptide antigens to T cells
- 16. a family name for cytokines that help cells to resist viral infections immunoglobulin a protein family to which antibodies and B-cell receptors belong
- 18. the most numerous white blood cells
- 20. The end stage of disease in HIV infection
- 21. it is a type of APC that presents antigen in the context of MHC to T cells
- 26. any of a class of proteins present in the serum and cells of the immune system which function as antibodies
- 29. a mononuclear phagocytic cell that circulates in the bloodstream and differentiates into macrophages in the tissue.
- 30. A transcription factor that causes several hundred tissue-specific genes to be transcribed by a subpopulation of epithelial cells in the thymus
- 31. a cytokine produced by macrophages and T cells that is highly pro-inflammatory
Down
- 2. Regulatory CD4+ T cells or called regulatory T cells (a T cell subset that is responsible for suppressing or limiting immune responses)
- 3. A cell that is able to present antigen via MHC molecules to T cell receptors on T cells
- 4. a lymphoid organ where T-cell maturation takes place
- 6. the internalization of particulate matter by phagocytotic cells
- 8. a group of substances which are secreted by certain cells of the immune system and have an effect on other cells
- 10. Immunoglobulin secreted by plasma cells
- 12. an abbreviation for receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
- 13. a group of white blood cells with multi-lobed nuclei and cytoplasmic granules
- 14. the general designation of many of the different cytokines, chemical messengers secreted by immune cells that help in their communication with other cells
- 17. a substance that promotes phagocytosis
- 19. is an acronym of Highly active anti-retroviral therapy
- 22. a complex system comprising a large number of proteins that act in concert to help eliminate infectious microorganisms
- 23. abbreviation for Cell adhesion molecule
- 24. Human immunodeficiency virus
- 25. A molecule that is recognized in native(original) structure by antibodies or B cell receptor (or a peptide that is presented by MHC molecules to T cell receptor)
- 27. an abbreviation for an autoimmune disease where autoantibodies (against DNA, RNA, and proteins associated with nucleic acids) form immune complexes
- 28. Human leukocyte antigen which is the name of MHC gene complex and proteins in humans