Across
- 4. pulp, this part of the spleen is where damaged red blood cells are removed from circulation
- 6. acronym for tissue that includes tonsils and Peyer's patches
- 7. this type of cell determines when the adaptive immune system needs to be activated
- 9. the death of this granulocyte is what leads to pus in your pimples
- 12. these types of leukocytes are also known as granulocytes
- 13. this type of cell is an effector B cell that secretes antibodies
- 14. acronym for amino acid sequence involved in signal transduction
- 16. patches, lymphoid follicles in the small intestine that make B cells (which give rise to IgA)
- 20. messenger proteins that bind receptors on effector cells to trigger an innate response
- 21. type of microorganisms detected in human feces via nucleic acid sequences
- 24. acronym for treatment for HIV infection involving multiple drugs
- 25. the process of the coating by an antibody (which increases phagocytosis)
- 26. acronym for the part of the antibody that contains the light chain and amino-terminal halks of the heavy chain di-sulfide bonded together
- 27. this granulocyte protects us from helminth worms
- 29. this type of immune response has long-lasting memory
- 30. a secondary lymphoid organ responsible for the immune response to blood-borne pathogens
Down
- 1. the part of an antigenic macromolecule that directly interacts with an antibody
- 2. the process of making white blood cells
- 3. the gland where T cells migrate to mature
- 5. acronym for a type of receptor that recognizes PAMPs on pathogens
- 8. acronym for a mechanism used by NK cells to induce apoptosis in infected cells
- 10. arise from lymphoid precursor cells; can be large or small
- 11. acronym for cell surface proteins that help cells stick to each other
- 15. these cells live permanently in the bone marrow and are precursors for platelets
- 17. this myeloid cell kills pathogens and recruits neutrophils by secreting cytokines
- 18. secreted by plasma cells
- 19. acronym for large lymphocyte that is also called a "cytotoxic" cell
- 22. this type of cell lives in connective tissue and contains chemical mediators that help eject parasites from the gut or respiratory tract
- 23. this type of immune response is our first line of defense
- 28. acronym for a name of proteins in humans and MHC gene complex
