Across
- 2. Organ in the body primarily responsible for producing complement proteins
- 4. Collective name for B and T cells
- 6. Immature progenitor cells that do not contain granules, circulate only in the blood, and can differentiate into dendritic cells or macrophages
- 7. Region of an antibody that binds to antigens, made up of light chain proteins
- 10. B and T cells that are "leftover" after clonal selection and easier to activate during a second attack with the same pathogen (2 words)
- 12. Region of an antibody that binds to receptors on the surface of cells, made up of heavy chain proteins
- 17. Group of well studied pattern recognition receptors; can be displayed either on the surface of cells or in the membranes of phago-lysosomes
- 18. Chemicals that recruit other immune system cells to the site of infection, such as C3a and C5a
- 19. Cells most associated with type I interferon production (abbreviation)
- 21. System composed of about 20 proteins that can be activated by the classical pathway, the alternative pathway, or the lectin activation pathway (2 words)
- 22. Surface receptors on an NK cell that interact with unusual carbohydrates/proteins and encourage the NK cell to kill (2 words)
- 23. Antibodies that bind to a virus while outside of a cell and prevent it from entering the cell (2 words)
- 24. Type of bacteria with a thin layer of peptidoglycan, an outer membrane, and LPS on the outermost surface of the cell wall (2 words)
- 26. Location in the body where all immune cells and blood cells originate from multipotent hematopoietic stem cells
- 27. Short lived cells that circulate in the blood and can migrate into the tissues when needed
- 28. Surface receptors on an NK cell that recognize class I MHC molecules on a cell surface and encourage the NK cell not to kill (2 words)
Down
- 1. These T cells kill virus infected cells by inspecting class I MHC molecules on the surface of cells in the body for peptides (3 words)
- 3. Contractions of these are necessary to circulate lymph throughout the body
- 5. Cytokine that is secreted by hyperactivated macrophages that can kill tumor cells and virus infected cells (abbreviation)
- 8. "Tester antibodies" anchored to the surface of a B cell that all recognize the same antigen
- 9. Type of bacteria with a very thick layer of peptidoglycan and teichoic acid on the outermost surface of the cell wall (2 words)
- 11. Second heaviest layer of blood, contains all the white blood cells
- 13. When an antibody binds to an invader and tags it for destruction, it ____s the invader
- 14. Nonliving assemblages of DNA/RNA that are the smallest of the 4 classes of pathogens
- 15. Cells with some characteristics of the innate immune system and some characteristics of the adaptive immune system, kills cells by forcing them to commit suicide (3 words)
- 16. Name for the cells in the body that make class II MHC molecules (abbreviation)
- 19. Process by which a B cell is triggered to double in size after binding to its cognate antigen
- 20. Structures in the blood that promote clotting and aid in healing and tissue repair
- 25. Granulocyte that contains collagenases to break down larger parasites