Immunology Exam Review

2. breaks down proteins into peptide fragments
3. the second stage in macrophage development
6. This is where T cells learn to tolerate the self
7. The first stage in macrophage development
9. can bind to an invader and mark it for destruction
10. Il-6, Il-23, and TGF-beta induce virgin T cells toward this path
11. act as foot soldiers in the immune response
12. After proliferation, some B cells become this and produce invader-specific antibodies
13. Cytokines produced by this Th cell include TNF, IFN-gamma, and Il-2
14. Macrophages secrete TNF and __ when they are hyperactivated, to influence NK cells to prime more macrophages
15. These antibodies bind to mast cells and cause runny nose and watery eyes upon second exposure to an allergen
16. both macrophages and neutrophils can secrete this
17. These cells rescue B cells from dying by apoptosis
18. usually, costimulation of T cells and APCs involves B7 on an APC plugging into __ on a T cell
19. Antibody-dependent cellular __ induces the NK cell to be more effective at killing
20. NK cells secrete this to prime macrophages
21. A process in which NK cells survey cells and destroy ones that don't display class 1 MHC

1. Help prevent the immune system from overreacting
2. Can help deactivate T cells
4. __ and CD8 receptors help focus Th cells and CTLs on the right MHC
5. After class switching occurs, this works to change the antibody gene that encodes the antigen-binding region
6. This Th class handles bacteria and parasites
8. dendritic cells travel to ___ to activate virgin T cells
15. Helps immune cells to ensure that only exogenous peptides are loaded into the groove of class 2 mhc
16. In tuberculosis tests, these proteins are injected into a patient
17. This can induce naive Th cells to become iTregs
22. These Toll-like receptors on dendritic cells sense viral RNA