Across
- 1. Regulator of complement activation which cleaves C3b. (2 words)
- 3. Converting a protein into peptides. (2 words)
- 5. Effector mechanism of antibody-mediated diseases due to neutrophils.
- 7. Meaning that many different alleles (variants) are present among the different individuals in the population.
- 9. Receptor found on B cells that is recognized by helper T cells.
- 13. Unresponsiveness of the adaptive immune system to antigens. (2 words)
- 18. Type of Class II MHC expressing APC responsible for priming. (2 words)
- 19. Type of hypersensitivity that causes hyperthyroidism. (3 words)
- 20. Genetically engineered receptors with tumor antigen-specific binding sites, type of therapy.
- 21. Structure that is recognized by the innate immune system and produced by microorganisms.
- 22. Type 4 hypersensitivity is mediated by these cells. (2 words)
- 24. What event occurs only within germinal centers? (2 words)
- 25. Type of antigen recognized in T-dependent antibody responses.
Down
- 2. Failure of self-tolerance is the cause of what disease?
- 4. What event utilizes the enzyme activation-induced deaminase? (2 words)
- 6. When a graft recipient’s T cells recognize intact donor HLA molecules on the surface of graft cells. (2 words)
- 8. A new protein that forms on cancer cells when certain mutations occur in tumor DNA.
- 10. Major component of the alternative pathway which gets cleaved by plasma protease. (2 words)
- 11. Transcription factor expressed by Regulatory T cells which essential for its development.
- 12. Type of hypersensitivity mediated by IgE antibodies.
- 14. Happens when an infectious microbe produces peptide antigens that are similar to self-antigens. (2 words)
- 15. Antibody present in a patient with blood type A.
- 16. Antibody employed against helminthic parasites.
- 17. Type of responsive T cell to Class I MHC molecule.
- 23. Antibody employed during mucosal immunity.