immunology intro

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Across
  1. 2. innate immunity response time
  2. 7. coordinated reaction of cells and molecules to foreign elements
  3. 8. P of PAMPs
  4. 10. segmented nucleus; pink granules; antiparasitic effectors
  5. 12. _____ immunity: non-specific; physical Barries, inflammation, complement
  6. 15. receptors of innate immunity that recognize PAMPs and DAMPs; soluble or membrane-bound; signaling or phagocytic
  7. 17. molecules that activate receptors; soluble or membrane bound
  8. 20. failure of immune system to distinguish between itself and foreign elements
  9. 21. released when cells die (intracellular) or generated when CT is damaged (extracellular)
  10. 22. expressed on the surface of a cell or in intracellular compartments
  11. 24. immunity that is only active when in contact with antigens
  12. 25. collection of cells, tissues, and molecules that mediate resistance to foreign elements
  13. 26. D of DAMPs
  14. 27. round nucleus, clear vacuolated cytoplasm, irregular shape; immune surveillance, antimicrobial, some antigen presentation
  15. 28. adaptive immunity response time
Down
  1. 1. communication between cells
  2. 3. chemotaxis
  3. 4. proteins with diverse functions: growth, activation
  4. 5. segmented nucleus; blue-purple granules; mediator of inflammation
  5. 6. cells round nucleus; cytoplasm is densely packed with purple granules; immune surveillance, mediator and amplifier of inflammation and allergy
  6. 7. _______ immunity: main cells -> macrophages, neutrophils, NK cells
  7. 9. round nucleus, clear cytoplasm, irregular shape with long branched projections; immune surveillance, antigen processing and presentation
  8. 11. round nucleus, very little clear cytoplasm; two types
  9. 12. study of immune system, including its responses to microbial pathogens and damaged tissues and its role in disease
  10. 13. _______ immunity: humoral and cellular
  11. 14. part of an antigen that is responsible for inducing the immune response and binding to the products of the immune response (lymphocyte receptors and antibodies)
  12. 16. components that are shared between different pathogens and present a molecular composition that differs from "self"
  13. 18. molecules that induce an immune response when introduced into the body
  14. 19. segmented nucleus, granular cytoplasm, fight bacterial infection
  15. 23. large lymphoid cell, round nucleus, azurophilic cytoplasmic granules; destruction of virally infected or abnormal host cells - tumor cells