Across
- 1. Pathogen-derived proteins that bypass conventional antigen processing and directly link T-cell receptors to MHC class II molecules, leading to massive T-cell activation
- 3. T lymphocytes identified by the CD8 coreceptor, primarily responsible for directly destroying virus-infected or cancerous cells
- 5. A specific type of T lymphocyte characterized by the presence of the CD4 coreceptor, vital for aiding other immune cells
- 7. The overarching genetic system responsible for cell-surface molecules crucial for T-cell antigen presentation
- 8. A diverse group of immune cells residing in barrier tissues, which, despite lacking antigen-specific receptors, are capable of rapid responses to pathogens and influence adaptive immunity
Down
- 2. A crucial thymic process that eliminates developing T cells exhibiting strong reactivity to self-components, preventing autoimmunity
- 3. A group/complex of integral membrane proteins closely associated with the T-cell receptor, essential for transducing signals into the T-cell upon antigen binding
- 4. The primary lymphoid organ where T lymphocyte precursors migrate from the bone marrow to undergo maturation
- 6. Immune cells, such as dendritic cells, B cells, and macrophages, that prepare antigens for recognition by T lymphocytes
- 9. Receptor on T cells for B7 expressed on antigen-presenting cells to provide a vital second activation signal