Important Acronyms of Immunology

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Across
  1. 1. A cell that is able to present antigen via MHC molecules to T cell receptors on T cells
  2. 3. Adaptive immune responses in which there is a major role for effector T cells
  3. 4. T type of APC that presents antigen in the context of MHC to T cells
  4. 5. Member of TNF receptor family expressed on certain cells that makes them susceptible to being killed by cells expressing the Fas ligand
  5. 7. A mechanism NK cells use to induce apoptosis in virally infected cells or tumor cells
  6. 8. SIg on B cells that binds Ag and transmits signal 1 to activate B cells.
  7. 10. Transcription factor expressed in Treg cells that is needed for Treg cell function
  8. 11. Immunoglobulin secreted by plasma cells
  9. 12. Cell adhesion molecule
  10. 14. Where Fc receptors bind
  11. 16. B lymphocyte that can differentiate into plasma cells secreting antibody molecules or B memory cells
  12. 17. Multiple drug treatment for HIV infection
  13. 19. The regions of the antigen binding loops of Ig molecules, antibodies and T cell receptors
  14. 21. T cells that express the co-receptor protein CD8 which differentiate into CTLs
Down
  1. 1. The end stage of disease in HIV infection
  2. 2. Cell-surface molecules on immune cells that help to differentiate one immune cell from another
  3. 5. The part of an antibody responsible for antigen binding
  4. 6. Crystallized fragment of antibody
  5. 7. A transcription factor that causes tissue-specific genes to be transcribed by epithelial cells in the thymus
  6. 9. Acute phase protein that binds to phosphocholine that can trigger Complement activation and acts as an opsonin
  7. 10. Cell surface receptors that bind to the Fc portion of IgG molecules
  8. 12. Family names of chemokine receptors
  9. 13. A virus that attacks the body's immune system
  10. 15. CD8+ T cells with the function of targeting and killing virally infected cells and tumor cells by apoptosis
  11. 18. A molecule that is recognized in native (original) structure by antibodies or receptors
  12. 19. T cells that express the co-receptor protein CD4 which differentiate into Thelper phenotypes
  13. 20. Family names of chemokines