Important Cardiology Clinical Trials

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Across
  1. 5. Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting for Severe Coronary Artery Disease
  2. 8. SGLT2 reduce the risk of hospitalization for heart failure and cardiovascular death among patients with HF mildly reduced EF
  3. 9. Reversed the paradigm rate first to rhythm first, early rhythm control reduces CV outcomes vs rate control alone
  4. 13. Eplerenone, as compared with placebo, reduced both the risk of death and the risk of hospitalization among patients with systolic heart failure and mild symptoms
  5. 14. Established Rate Control as first step in AF
  6. 15. First time combo of low dose NOACs + Antiplatelet reduces cardiovascular events in stable CAD
Down
  1. 1. First trial showed that inflammation reduction improves CV outcomes
  2. 2. Introduced ARNI IN HF
  3. 3. No mortality benefit with early invasive strategy vs optimal medical therapy in stable CAD
  4. 4. Shifted SGLT2i from Diabetes to Heart Failure
  5. 6. TAVI versus Surgical Aortic-Valve Replacement
  6. 7. Reperfusion involving the transfer of patients to an invasive-treatment center for primary angioplasty is superior to on-site fibrinolysis, provided that the transfer takes two hours or less
  7. 10. Patients receiving empagliflozine had a lower risk of CV death or hospitalization for heart failure than those in the placebo group, regardless of the presence or absence of diabetes
  8. 11. PCSK9i into Lipid Guidelines
  9. 12. MRA benefit in HFpEF