Influenza Virus

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Across
  1. 1. the _____ period for influenza virus is 18-72 hours
  2. 3. method by which viral components are released from the cell
  3. 4. type of vaccine used for prevention of influenza virus
  4. 5. M1 protein that forms rigid outer shell to protect the virus
  5. 6. shape of capsid
  6. 11. first individual to describe influenza-like symptoms as early as 412 B.C.
  7. 13. occurs when new cases of a disease in a given population exceeds steady-state norm
  8. 14. most common complication of influenza
  9. 16. method of entry into the host cell
  10. 21. A type of influenza associated with pandemics
  11. 23. enzyme which catalyzes glycosidic breakdown and assists viral exit from the host cell after multiplication
  12. 25. shape of hemagglutinin as seen from electron micrographs
  13. 27. infection with the influenza virus leads to increased _____ production
  14. 30. member of this family
  15. 37. number of viral proteins encoded by the genome
  16. 38. type of antigenic shift involving crossover recombination
  17. 39. influenza virus is divided into __ major classes
  18. 40. common clinical symptom characterized by abnormally high body temperature
  19. 42. structural motif found at the end of each vRNA segment
  20. 43. type of antigenic shift involving segment exchange recombination
  21. 44. method of infection transmission
  22. 46. trimeric glycoprotein found in the membrane envelope which assists in host cell attachment
  23. 47. lab test used to diagnose influenza
  24. 48. structure of virus genome
  25. 50. how often should influenza vaccines be administered
Down
  1. 2. enzyme inhibited by therapeutic agents such as Tamiflu
  2. 7. process in which 2 or more viruses infect a single host and exchange genetic material
  3. 8. high _____ rates allow circumvention of the immune system
  4. 9. season in which influenza epidemics occur regularly
  5. 10. steady-state maintenance of infection rate in a population without external input
  6. 12. contained in the host nucleus, essential for mRNA viral synthesis
  7. 15. shift major change in the influenza virus which usually leads to global influenza pandemics
  8. 17. shape of the viral genome
  9. 18. acid receptor molecule for influenza virus
  10. 19. variable in size and shape
  11. 20. antibody class mainly responsible for immune response to influenza
  12. 22. type of RNA found in the genome
  13. 24. number of segments in the viral genome
  14. 26. global outbreak
  15. 28. Flu major influenza pandemic which occurring in 1918
  16. 29. term influenza originated from the Italian word meaning ____
  17. 31. drift minor change in properties of influenza virus that make existing vaccines less or noneffective
  18. 32. type of virus in which the nucleocapsid is surrounded by a lipid bilayer
  19. 33. molecule consisting of protein and carbohydrates
  20. 34. cells in which influenza viruses replicate
  21. 35. animal species that acts as a “natural reservoir” for influenza virus
  22. 36. signaling protein released in response to infection with influenza virus
  23. 41. common type of infection caused by influenza viruses
  24. 45. age group with highest rate of infection
  25. 49. after endocytosis the virion fuses with the _____