Influenza Virus

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Across
  1. 6. enzyme responsible for antigenic drift
  2. 8. inhibits translation
  3. 9. influenza season begins in
  4. 12. this influenza symptom can cause dehydration
  5. 17. these carbohydrates contain sialic acid
  6. 18. the active ingredient in this medication is baloxavir marboxil
  7. 19. interferons are released when the immune system detects viral ____
  8. 20. kind of medications used to combat influenza
  9. 25. an enzyme involved in viral replication
  10. 29. peramivir is eliminated in the ____
  11. 30. the virus has ___-sense genome
  12. 31. minimum units required for viral replication
  13. 35. Type A influenza is the most _____
  14. 38. best method for testing if one has the virus
  15. 40. medication that is a M2 proton channel antagonist
  16. 44. when PB2 bings to host mRNA, this step begins
  17. 46. can suggest coinfection with bacteria
  18. 47. ligand for RIG-I
  19. 48. influenza changes its genome using ______ shift
Down
  1. 1. new antigenic subtypes can cause a global ___
  2. 2. a glycoprotein that helps the virus enter the cell
  3. 3. transcription enzyme
  4. 4. percent of world affected by the virus each year
  5. 5. the shape of the virion can be spherical or _______
  6. 7. the environment of the virion is ____
  7. 10. generic name of Tamiflu
  8. 11. protein expression of the virus occurs in this part of a cell
  9. 13. best way to prevent catching the virus
  10. 14. clear virus-infected cells from the body
  11. 15. people that have an allergy to ___ should not take zanamivir
  12. 16. has a role in virus budding
  13. 21. Type C influenza can cause ___ in animals
  14. 22. generic name of Relenza
  15. 23. influenza replicates in this kind of cell
  16. 24. site within a cell where viral replication occurs
  17. 26. Quadrivalent vaccines without ___ are approved for ages > 6 months
  18. 27. this kind of T cell helps clear influenza from the body
  19. 28. the age group most vulnerable due to influenza
  20. 32. influenza is a member of the _____ family
  21. 33. influenza uses ___ in its genome
  22. 34. A complication from influenza during pregnancy
  23. 35. cause inflammation seen in patients from the virus
  24. 36. this substance covers the epithelium in the respiratory system
  25. 37. M2 is a ______ protein which forms an ion channel
  26. 39. zanamivir works by _______ the enzyme neuraminidase
  27. 40. prevent reinfection from the same strain
  28. 41. type of influenza which occurs in wild birds
  29. 42. acid virions bind to receptors containing ____
  30. 43. this neuraminidase inhibitor is long acting
  31. 45. route of transmission