Innate Immunity

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Across
  1. 3. an RNA helicase that recognize dsRNA in the cytoplasm
  2. 5. cells that phagocytize infected cells and inactivate extracellular viruses
  3. 6. play a very small role in the inactivating viruses
  4. 9. interferon produced by epithelial cells
  5. 11. promotes phagocytosis and induce lysis of microbes
  6. 14. programmed cell death an intrinsic response of infected cells
  7. 15. interferon produced by T and NK cells
  8. 16. PRR that recognizes CPG motifs in viral DNA
  9. 17. first cells that responds to a viral infection
  10. 18. physical intrinsic barrier against infection
Down
  1. 1. key antigen-presenting cells for induction of adaptive immunity
  2. 2. a type of immunity you are born with
  3. 4. antiviral cytokines
  4. 7. bridges innate and adaptive immunity
  5. 8. PRR that recognizes dsRNA within endosomes
  6. 10. interferon produced by most if not all nucleated cells
  7. 12. pattern recognition receptors (PRR) within cellular endosomes that sense foreign molecules
  8. 13. interferon stimulated genes that establish antiviral state