Innate immunity, Complement

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Across
  1. 2. membrane attack complex, shortcut
  2. 5. they are involved in classical complement pathway
  3. 6. non-self microbial structures, eg.LPS, shortcut
  4. 9. they are involved in lectin complement pathway
  5. 11. C3a or C5a
  6. 13. quick pathway of complement activation
  7. 14. class of antibodies involved in classical complement pathway
  8. 15. the region of the antibody to which C1q binds
  9. 16. C3b
  10. 19. antimicrobial peptides produced by epithelial cells
  11. 20. molecular shape; antibody changes it after the antigen binds
Down
  1. 1. C3a, C5a & C4a
  2. 3. acute phase protein involved in the classical complement pathway
  3. 4. bactericidal enzyme found in secretions
  4. 7. lectin produced in liver, found in serum
  5. 8. spaniel, a breed of dog with C3 deficiency
  6. 10. cells degranulated by C3a and C5a
  7. 11. most abundant serum component of the complement system
  8. 12. this is where the complement proteins are made
  9. 17. Gram-.... bacteria are resistant to complement
  10. 18. immunity found in invertebrates and vertebrates