Intro to Immunology, Antigens, and MHC

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Across
  1. 2. Substance administered with an immunogen that enhances immune response
  2. 7. Alternate form of a gene that codes for a slightly different form of the same product
  3. 8. Condition of being resistant to infection
  4. 9. bone marrow and thymus, where lymphocytes mature
  5. 11. Macromolecule that stimulates production of antibodies or sensitized lymphocytes
  6. 12. Set of genes located close together on a chromosome, usually inherited as a single unit
  7. 16. Process of producing nonpathogenic bacteria or viruses for use in vaccines
  8. 17. Immunoglobins, a glycoprotein produced by B and plasma cells due to foreign exposure
  9. 19. engulfment of cells or particulate matter by WBCs
  10. 20. Ability of an immunogen to stimulate a host response
  11. 22. Host’s antigen and is incapable of stimulating an immune response under normal conditions
  12. 23. protection from disease caused by antibodies in serum
Down
  1. 1. type of resistance to infection by antigen specificity due to prior exposure
  2. 3. Antigen found in another member of host’s species that elicits an immune response
  3. 4. Protein coded for by the MHC genes that plays an essential role in the immune response and rejection of foreign transplants
  4. 5. Portion of the immunogen against which the immune response is directed
  5. 6. Process by which degraded peptides within cells are transported to the plasma membrane with MHC molecules so that T cells can recognize them
  6. 10. Substance capable of inducing an immune response
  7. 13. organs where main contact with foreign antigens take place (ex: lymph nodes)
  8. 14. Antigen in different species but is identical or similar it causes cross-reactivity
  9. 15. Proteins coded for by genes at loci A, B, C in the MHC and Expressed on all nucleated cells
  10. 18. Proteins coded for by genes at loci DR, DP and DQ in the MHC and Found on B cells, macrophages, activated T cells, monocytes, dendritic cells & endothelium
  11. 21. ability of individual to resist infection naturally